Clinical Observation on Facial Scrapping Combined with External Application of Tranexamic Acid Solution in the Treatment of Melasma
Objective:To observe the clinical efficacy of facial scraping combined with topical application of tranexamic acid solution in the treatment of chloasma.Methods:A total of 60 female patients with chloasma were ran-domly divided into a control group(n=30)and an observation group(n=30).The control group was treated with topi-cal application of tranexamic acid solution,and the observation group was treated with facial scraping on the basis of the control group.The treatment time of both groups was 12 weeks.The changes in skin lesion area and color score,dermatology life quality index score(DLQI)before and after treatment and satisfaction with the treatment effect were compared between the two groups.Results:After treatment,the skin lesion area and color score,and DLQI score of the two groups were reduced compared with those before treatment,with statistical differences;after treatment,the skin le-sion area color score and DLQI score of the observation group were significantly lower than those of the control group,with statistical differences;the satisfaction rate of the control group was significantly lower than that of the observation group,with statistical differences.Conclusion:Facial scraping combined with topical application of tranexamic acid so-lution is safe and effective in the treatment of chloasma,and patients have high satisfaction.
万方数据
维普
