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复方莪术散治疗恶性肿瘤高凝状态的临床研究

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目的:观察复方莪术散改善恶性肿瘤高凝状态的临床疗效;方法:收集恶性肿瘤并血液高凝状态的患者 60 例,随机分为对照组 30 例(脱落 1 例),剩余 29 例,治疗组 30 例,对照组采用常规对症支持治疗,治疗组在常规对症支持治疗的基础上加用复方莪术散,以两周为一个治疗周期;检测治疗前后 2 组患者外周血的D-二聚体(DD)、纤维蛋白原含量(FIB)、血浆凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)、血小板计数,并记录中医证候积分,生活质量评分;结果:复方莪术散可以降低恶性肿瘤并血液高凝状态的患者的DD,改善FIB、PT、APTT,提高生活质量,说明复方莪术散治疗恶性肿瘤并血液高凝状态有效.
Compound Zedoary Turmeric Powder for Treating Hypercoagulability of Malignant Tumor
Objective:To observe the clinical efficacy of compound curcuma powder in improving the hypercoagu-lable state of malignant tumors.Methods:A total of 60 patients with malignant tumors and hypercoagulable state were collected and randomly divided into a control group of 30 cases(1 case dropped out)and the remaining 29 cases,and a treatment group of 30 cases.The control group received conventional symptomatic supportive treatment,and the treat-ment group was treated with compound curcuma powder on the basis of conventional symptomatic supportive treatment,with a treatment cycle of two weeks.The peripheral blood D-dimer(DD),fibrinogen content(FIB),plasma prothrombin time(PT),activated partial thromboplastin time(APTT),and platelet count of the two groups of patients before and after treatment were detected,and the TCM syndrome score and quality of life score were recorded.Results:Compound cur-cuma powder can reduce DD,improve FIB,PT,APTT,and improve the quality of life of patients with malignant tumors and hypercoagulable state,indicating that compound curcuma powder is effective in treating malignant tumors and hy-percoagulable state.

Compound Ezhu powderMalignant tumorHypercoagulable state

郝家鹏、杨天明、杜平、陈燕、郭茂新、李艳

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贵州省毕节市中医医院 贵州 毕节 551700

贵州中医药大学 贵州 贵阳 550000

复方莪术散 恶性肿瘤 高凝状态

2024

中医药临床杂志
中华中医药学会

中医药临床杂志

影响因子:0.636
ISSN:1672-7134
年,卷(期):2024.36(11)