Discussion on Chinese Medicine Diagnosis and Treatment of Hepatomegaly Insomnia based on the Theory of"Harmony of Liver and Heart
Wilson's disease(WD)is an autosomal recessive genetic disease caused by ATP7B gene mutation.Its main pathogenesis is the disorder of ceruloplasmin synthesis,copper cannot be excreted from bile,and copper is de-posited in various organs,resulting in pathological changes.Insomnia is a common non-motor symptom of WD.Tra-ditional Chinese medicine believes that insomnia belongs to the category of"insomnia",which is often related to the heart,liver,and kidney.Heart yang deficiency,kidney water deficiency,and liver depression are all causes of insom-nia.The"liver-heart harmony"theory was first proposed and applied to"double heart disease".In recent years,it has been used as a treatment idea for insomnia.Based on traditional Chinese medicine theory and modern clinical research,this article discusses the basis and clinical application points of the"liver-heart harmony"theory for the diagnosis and treatment of WD insomnia,and provides new ideas and methods for the diagnosis and treatment of WD insomnia in tra-ditional Chinese medicine.
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