首页|清肺化痰汤联合西药治疗痰热壅肺型支气管扩张症

清肺化痰汤联合西药治疗痰热壅肺型支气管扩张症

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目的:探究清肺化痰汤联合西药治疗痰热壅肺型支气管扩张症的疗效及对炎症指标的影响.方法:选取符合标准的支气管扩张症患者 82 例,根据治疗方案分组,对照组 45 例患者采用西医常规治疗,观察组 37 例患者在对照组基础上联用清肺化痰汤治疗,所有患者的疗程均为 10~14d.将 2 组患者的中医证候积分、临床疗效、炎症指标、肺功能以及不良反应发生情况进行对比分析.结果:2 组患者在治疗前比较,各项指标差异均不显著(P>0.05).在治疗之后,观察组患者的临床总有效率、第 1 秒用力呼气容积(FEV1)以及FEV1/用力肺活量(FVC)均明显高于对照组(P<0.05);中医证候总积分、C反应蛋白(CRP)、降钙素原(PCT)水平、不良反应总发生率均明显较对照组低(P<0.05).结论:对于患有痰热壅肺型支扩的病人,采用清肺化痰汤与西药的联合疗法,临床疗效确切,可显著降低患者机体炎症指标水平及不良反应发生率,同时可有效改善患者肺功能,具有较高的临床应用价值.
therapeutic Efficacy and Effect on Inflammatory Indexes in the treatment of Phlegm-heat Congested Lung Type Bronchiectasis by Qingfei Huatan Decoction Combined with Western Medicine
Objective:To explore the efficacy of Qingfei Huatan Decoction combined with western medicine in the treatment of bronchiectasis with phlegm-heat blocking the lungs and its effect on inflammatory indicators.Methods:82 patients with bronchiectasis who met the criteria were selected and divided into groups according to the treatment plan.45 patients in the control group were treated with conventional Western medicine,and 37 patients in the observation group were treated with Qingfei Huatan Decoction on the basis of the control group.The results of all patients The du-ration of treatment is 10 to 14 days.The TCM syndrome scores,clinical efficacy,inflammatory indicators,lung function and occurrence of adverse reactions were compared and analyzed between the 2 groups of patients.Results:Compar-ing the two groups of patients before treatment,the differences in various indicators were not significant(P>0.05).After treatment,the total clinical effective rate,forced expiratory volume in 1 second(FEV1)and FEV1/forced vital capacity(FVC)of the observation group were significantly higher than those of the control group(P<0.05);the total TCM syn-drome score,C The levels of reactive protein(CRP),procalcitonin(PCT),and the total incidence of adverse reactions were significantly lower than those in the control group(P<0.05).Conclusion:For patients with bronchiectasis due to phlegm-heat congesting the lungs,the combined therapy of Qingfei Huatan Decoction and western medicine has defi-nite clinical efficacy.It can significantly reduce the level of inflammatory indicators and the incidence of adverse reac-tions in patients,and at the same time,it can effectively improve The patient's lung function has high clinical applica-tion value.

Qingfei Huatan DecoctionPhlegm-Heat blocking lung typeBronchiectasisEfficacyInflammatory in-dex

丁品品、顾楠、刘秋卉

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南京中医药大学常州附属医院,常州市中医医院 江苏 常州 213000

江苏省常州市武进中医医院 江苏 常州 213161

清肺化痰汤 痰热壅肺型 支气管扩张症 疗效 炎症指标

2024

中医药临床杂志
中华中医药学会

中医药临床杂志

影响因子:0.636
ISSN:1672-7134
年,卷(期):2024.36(12)