首页|杜藤颗粒口服联合五味骨疽拔毒散外敷治疗膝骨关节炎疗效观察

杜藤颗粒口服联合五味骨疽拔毒散外敷治疗膝骨关节炎疗效观察

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目的:探讨杜藤颗粒联合五味骨疽拔毒散在治疗膝骨关节炎中的应用及疗效,以期为临床用药提供一定参考.方法:选取符合标准的膝骨关节炎患者 60 例,随机分为观察组和对照组,各 30 例.对照组予塞来昔布口服,观察组在对照组基础加用杜藤颗粒口服和五味骨疽拔毒散外敷.共治疗 4 周,比较 2 组治疗前后疼痛视觉模拟评分(VAS评分)、WOMAC骨关节炎指数评分、雷瑟曼膝关节评分(Lysholm)以及临床疗效.结果:治疗后,2 组的VAS和WOMAC评分均降低(P<0.05),Lysholm评分均升高(P<0.05),而观察组评分明显优于对照组(P<0.05).结论:杜藤颗粒内服联合五味骨疽拔毒散外用治疗可有效改善膝骨关节炎患者膝关节功能,提升治疗效果,提高患者生活质量.
Observation on the Curative Effect of Oral Duteng Granule Combined with Wuwei Guju Badu Powder on Knee Osteoarthritis
Objective:To explore the application and efficacy of Duteng granules combined with Wuwei Guju Badu powder in the treatment of knee osteoarthritis,in order to provide a certain reference for clinical medication.Methods:A total of 60 patients with knee osteoarthritis who met the criteria were selected and randomly divided into an observa-tion group and a control group,30 cases in each group.The control group was given celecoxib orally,and the observa-tion group was given Duteng granules orally and Wuwei Guju Badu powder externally on the basis of the control group.The treatment lasted for 4 weeks,and the pain visual analogue scale(VAS score),WOMAC osteoarthritis index score,Lysholm knee score(Lysholm)and clinical efficacy were compared between the two groups before and after treatment.Results:After treatment,the VAS and WOMAC scores of the two groups were reduced(P<0.05),and the Lysholm scores were increased(P<0.05),and the scores of the observation group were significantly better than those of the con-trol group(P<0.05).Conclusion:Oral administration of Duteng granules combined with external application of Wuwei Guju Badu powder can effectively improve the knee joint function of patients with knee osteoarthritis,enhance the treatment effect,and improve the quality of life of patients.

Duteng granulesWuwei Guju Badu powderKnee osteoarthritis

白增辉、陈斌

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安徽中医药大学第一临床医学院 安徽 合肥 230031

安徽中医药大学第一附属医院 安徽 合肥 230031

杜藤颗粒 五味骨疽拔毒散 膝骨关节炎

2024

中医药临床杂志
中华中医药学会

中医药临床杂志

影响因子:0.636
ISSN:1672-7134
年,卷(期):2024.36(12)