Effect of External Application of Zibing Chuangyu Ointment on the Wound after Milligan-Morgan Hemorrhoidectomy for Mixed Hemorrhoids
Objective To investigate the effect of external application of Zibing Chuangyu Ointment on the wound after Milli-gan-Morgan hemorrhoidectomy for mixed hemorrhoids.Methods A total of 70 patients with mixed hemorrhoids were random-ly divided into observation group and control group,with 35 patients in each group.The patients in both groups were given symptomatic treatment such as anti-infective therapy and pain-relieving therapy after surgery,and in addition,the patients in the observation group were given Zibing Chuangyu Ointment for dressing change,while those in the control group were given Gangtai Ointment.On days 1,4,7,and 14 after surgery,the serum level of vascular endothelial growth factor (VEGF)was measured;Visual Analogue Scale (VAS)was used to assess the degree of pain;the wound was observed in terms of wound ex-udates,wound edge edema,growth of granulation tissue,and wound healing conditions.Results On days 4,7,and 14 after surgery,the observation group had a significantly higher serum level of VEGF than the control group (P<0.05).Compared with the control group,the observation group had lower or significantly lower VAS pain score,wound exudate score,granula-tion tissue score,wound edge edema score,and wound area (P>0.05 orP<0.05).Conclusion External application of Zib-ing Chuangyu Ointment can alleviate wound pain,reduce wound exudates and wound edge edema,promote the growth of gran-ulation tissue,and facilitate wound healing after Milligan-Morgan hemorrhoidectomy for mixed hemorrhoids.
万方数据
维普
