摘要
目的 观察腕踝针促进胃肠道恶性肿瘤术后胃肠功能恢复的临床疗效.方法 将62例胃肠道恶性肿瘤患者,采用随机数字表结合信封法分为观察组和对照组,每组31例.对照组给予常规手术治疗及对症治疗;观察组在对照组治疗基础上,待手术结束患者苏醒时,即行腕踝针干预治疗;疗程结束后观察两组患者胃肠功能恢复情况、胃肠激素分泌水平、创面疼痛评分和营养状况改善情况.结果 观察组患者肠鸣音恢复时间、排气排便时间以及进食时间均较治疗组显著缩短(P<0.05).术后1 d,观察组血清胃蛋白酶Ⅱ水平较对照组显著降低(P<0.05);术后3 d,观察组血清胃蛋白酶Ⅰ、胃蛋白酶Ⅱ水平均较对照组显著降低(P<0.05),观察组血清胃泌素-17水平较对照组有所升高(P>0.05).与对照组比较,观察组术后1、3 d创面疼痛VAS评分均显著减少(P<0.05).术前、术后1 d、术后3 d两组患者总蛋白、白蛋白、血红蛋白水平比较,差异均无统计学意义(P>0.05).结论 腕踝针对胃肠道恶性肿瘤术后胃肠功能恢复具有较好的临床疗效.
Abstract
Objective To investigate the clinical effect of wrist-ankle acupuncture in promoting the recovery of gastrointestinal function after surgery for gastrointestinal malignant tumors.Methods A total of 62 patients with gastrointestinal malignant tumors were divided into observation group and control group using a random number table and the envelope method,with 31 patients in each group.The patients in the control group received conventional surgical treatment and symptomatic treatment,and in addition to the treatment in the control group,those in the observation group received wrist-ankle acupuncture immedi-ately after recovery from general anesthesia.After the treatment ended,the two groups were observed in terms of the recovery of gastrointestinal function,the secretion of gastrointestinal hormones,wound pain score,and the improvement in nutritional status.Results Compared with the control group,the observation group had significantly shorter time to first bowel sound,time to first flatus,time to first defecation,and time to diet(P<0.05).On day 1 after surgery,compared with the control group,the observation group had a significant reduction in the serum level of pepsin Ⅱ(P<0.05);on day 3 after surgery,compared with the control group,the observation group had significant reductions in the serum levels of pepsin Ⅰ and pepsin Ⅱ(P<0.05)and an increase in the serum level of gastrin-17 (P>0.05). Compared with the control group,the observation group had a significant reduction in the visual analogue scale score of wound pain on days 1 and 3 after surgery (P<0.05). There were no significant differences between the two groups in the levels of total protein,albumin,and hemoglobin before sur-gery and on days 1 and 3 after surgery (P>0.05). Conclusion Wrist-ankle acupuncture has a good clinical effect on the re-covery of gastrointestinal function after surgery for gastrointestinal malignant tumors.
基金项目
"十二五"国家临床重点专科建设项目胃肠肿瘤专项(财社[2013]239号)
国家中医药管理局重点专科胃肠肿瘤专项(国中医药医政发[2012]2号)
维普
万方数据