首页|火针联合浆乳二号方治疗非哺乳期乳腺炎脓肿期临床研究

火针联合浆乳二号方治疗非哺乳期乳腺炎脓肿期临床研究

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目的 观察火针联合浆乳二号方治疗非哺乳期乳腺炎(non-puerperal mastitis,NPM)脓肿期的临床疗效.方法 将90例NPM患者按1∶1比例随机分为试验组(n=45)和对照组(n=45).两组均口服浆乳二号方,对照组配合穿刺抽脓或切开排脓,试验组给予火针治疗,疗程12周.治疗前和治疗后不同时点,分别观察两组患者乳房脓肿面积,乳房肿块面积、体积,乳房疼痛数字评定量表(numerical rating scale,NRS)评分,以及白细胞(white blood cell,WBC)计数、中性粒细胞百分比(neutrophil percentage,N%)、C-反应蛋白(C-reactive protein,CRP)水平;治疗12周末评价乳房外形,治疗期间观察治疗方法的安全性.结果 试验组、对照组分别脱落2、3例.治疗后两组患者乳房脓肿面积,乳房肿块面积、体积均较治疗前显著缩小(P<0.05),乳房疼痛NRS评分、WBC计数、N%、CRP水平均显著降低(P<0.05);试验组WBC计数、N%下降程度显著大于对照组(P<0.05);试验组在缩小乳房脓肿面积,肿块面积、体积,乳房疼痛NRS评分方面显著优于对照组(P<0.05);治疗12周末,试验组乳房外形评价结果显著优于对照组(P<0.05);治疗期间两组均未发生明显不良事件.结论 火针联合浆乳二号方对NPM脓肿期有排脓消肿的作用,可减轻乳房疼痛,抑制NPM炎症反应,起效快,创伤小,无明显不良反应.
Clinical Efficacy of Fire Needle Combined with No.2 Decoction for Plasma Cell Mastitis in Treatment of Non-puerperal Mastitis in the Abscess Stage
Objective To investigate the clinical efficacy of fire needle combined with No.2 Decoction for plasma cell mastitis in the treatment of non-puerperal mastitis (NPM)in the abscess stage.Methods A total of 90 patients with NPM were ran-domly divided into experimental group and control group at a ratio of 1∶1,with 45 patients in each group.Both groups were given oral administration of No.2 Decoction for plasma cell mastitis,and in addition,the patients in the control group were given puncture for pumping pus or incision and drainage,while those in the experimental group were given fire needle therapy.The course of treatment was 12 weeks for both groups.The two groups were observed in terms of the area of breast abscess,the area and volume of breast mass,the numerical rating scale (NRS)score for breast pain,white blood cell count (WBC),neutrophils percentage (N%)and C-reactive protein (CRP)level at different time points before and after treatment.The shape of the breast was evaluated at the end of week 12,and the safety of the treatment method was observed during treatment.Results Two patients in the experimental group and 3 in the control group were lost to follow-up.After treatment,both groups had significant reductions in the area of breast abscess,the area and volume of breast mass,the NRS score for breast pain,WBC,N%,and CRP level (P<0.05).Compared with the control group,the experimental group had significantly grea-ter reductions in WBC and the percentage of neutrophils (P<0.05)and significantly better results of the reductions in the area of breast abscess,the area and volume of breast mass,and the NRS score for breast pain (P<0.05).At the end of week 12,the experimental group had significantly better evaluation results of breast shape than the control group (P<0.05).No obvi-ous adverse events were observed in either group during treatment.Conclusion Fire needle combined with No.2 Decoction for plasma cell mastitis can reduce breast abscess and eliminate swelling in the abscess stage of NPM,thereby alleviating breast pain and inhibiting inflammatory response in NPM,with a rapid onset of action and little trauma,and there are no obvious ad-verse events.

Non-puerperal mastitisAbscess stageFire needleNo.2 Decoction for plasma cell mastitis

郑洁莹、仲文莉、王玥琦、陈颖、陆钰原、尚汇渊、夏仲元

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北京中医药大学,北京 100029

中日友好医院中医外科,北京 100029

北京市朝阳区中西医结合急诊抢救医院乳腺科,北京 100029

非哺乳期乳腺炎 脓肿期 火针疗法 浆乳二号方

2024

安徽中医药大学学报
安徽中医学院

安徽中医药大学学报

CSTPCD
影响因子:0.796
ISSN:2095-7246
年,卷(期):2024.43(6)