In order to make effective use of domestic sewage in oil field production enterprises,21 stations that can use domestic sewage for desert vegetation ir-rigation were selected in an oil field enterprise.Com-bining the basic conditions of each sewage station and the distribution of surrounding desert vegetation,San-ji sewage treatment station was selected as the re-search sample point.The effects of oilfield domestic wastewater on groundwater,soil and vegetation for desert vegetation irrigation were studied.The experi-mental results showed that after one year of drip irri-gation and spray irrigation,the surrounding vegeta-tion grew well,the environmental quality of groundw-ater and soil changed little,and there was no deterio-ration phenomenon.