癌症进展2012,Vol.10Issue(2) :170-173.DOI:10.3969/j.issn.1672-1535.2012.02.014

低级别胶质瘤继发癫痫术前综合评估的重要性

The importance of preoperative comprehensive evaluation for low-grade gliomas with secondary epilepsy

于世林 赵媛 程晓刚
癌症进展2012,Vol.10Issue(2) :170-173.DOI:10.3969/j.issn.1672-1535.2012.02.014

低级别胶质瘤继发癫痫术前综合评估的重要性

The importance of preoperative comprehensive evaluation for low-grade gliomas with secondary epilepsy

于世林 1赵媛 2程晓刚3
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作者信息

  • 1. 北京老年医院内分泌科,北京100095
  • 2. 中国医科大学北京顺义医院神经内科,北京101300
  • 3. 成都医学院免疫学教研室,成都610083
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摘要

目的 分析低级别胶质瘤继发癫痫术前评估的重要性.方法 回顾性分析42例低级别胶质瘤继发癫痫患者术前评估的临床资料进行统计学分析.结果 头磁共振成像(MRI)、视频脑电图(V-EEG)、脑正电子发射断层扫描(PET)三种检查结果定位一致的阳性率高于V-GGE和脑PET,差异具有统计学意义(P<0.05).术后1年和2年发作减少的有效率均为100%.结论 术前通过影像学、视频脑电图及脑PET检查的综合评估,可早期进行手术治疗,从而提高癫痫手术效果.

Abstract

Objective To compare the efficacy and safely of domeslic clopidogrel (Talcom ) and imported clopidogrel ( Plavix ) on direcled PCI in AMI palienls. Methods 204 palienls with AMI Lo undergo direcled CAG + PCI were divided lo Iwo groups, including Talcom(TM) group (n = 123) and Plavix(TM) group ( n = 81) . 300 mg loading dose clopidogrel was oral before PCI in emergency room and 75 mg/d foreword one year. There were follow - up 3 ~ 28 monlh lo survey ihe incidence rale of MACE of combinalion end poinl of acute, subacule, lale slage, very lale slage slenl ihrombus and AMI, cardiac dealh, slroke and correlaled adverse reaction of bleed, major bleed, gaslroinleslinal complaint, and elc. Results There were nol slenl ihrombus and bleed evenl bolh Talcom(TM) group and Plavix(TM) group. There are Iwo palienls dealh of cardiac shock and heart ruplure in Plavix(TM) group. There were no significant differences in ihe incidence of targel vessel revascularization and combinalion end point belween Talcom? group and Plavix? group (X2 value 0. 000 and 0. 921 ,P value 0. 989 and 0. 337) . There were no significant differences in accumulation MACE hazard analysis by Kaplan - Meier survival analysis (X20.679, P =0.410). Conclusion Effecls and safely of isodose Talcom(TM) used in AMI palienls thal underwent emergenl direcled PCI are similar Lo those of Plavix(TM).

关键词

低级别胶质瘤/癫痫/术前评估

Key words

Clopidogrel/PercuLaneous coronary inlervenlions(PCI)/Clinical conlrol Lrail/EffecL/Safely/AcuLe myocardial infarclion(AMI)

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出版年

2012
癌症进展
中国医学科学院,北京协和医学院

癌症进展

CSTPCD
影响因子:1.004
ISSN:1672-1535
被引量6
参考文献量2
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