Analysis of influencing factors for postoperative recurrence risk of basal cell carcinoma of eyelid
Objective To analyze the influencing factors for postoperative recurrence risk of basal cell carcinoma of eyelid(EBCC).Method A total of 66 patients with EBCC were collected,and the expression of transmembrane protein 16A(TMEM16A),Ki-67,integrin linked kinase(ILK)were detected by immunohistochemistry.Followed up for 2 years,the recurrence rate of EBCC patients were recorded,and the influencing factors of recurrence of EBCC patients were ana-lyzed by multiple Logistic regression.Result After 2 years follow-up,among 66 patients of EBCC,20 patients were re-currenced,while 46 patients did not,the recurrence rate was 30.30%(20/66).The age,smoking history,alcohol con-sumption history,family history,interleukin-6(IL-6)levels,interleukin-1β(IL-1β)levels,transforming growth factor-1β(TGF-1β)levels,TMEM16A positive expression,Ki-67 positive expression,and ILK positive expression were different between recurrent and non-recurrent EBCC patients(P<0.05).Multiple Logistic regression analysis showed that smoking history,alcohol consumption history,IL-6≥70 pg/ml,TMEM16A positive expression,Ki-67 positive expression,and ILK positive expression were independent risk factors for recurrence in EBCC patients(P<0.05).Conclusion Smoking histo-ry,alcohol consumption history,IL-6≥70 pg/ml,TMEM16A positive expression,Ki-67 positive expression,and ILK posi-tive expression are all independent risk factors for recurrence in EBCC patients.
basal cell carcinoma of eyelidtransmembrane protein 16AKi-67integrin linked kinaserecurrencerisk factor
NETL
NSTL
万方数据
维普
