Target delineation of whole-breast prophylactic irradiation after breast conserving surgery
Objective To explore the target delineation of whole-breast prophylactic irradiation after breast conserv-ing surgery.Method A total of 149 patients with breast cancer were selected,all patients underwent MRI examination,and the location of breast cancer lesions were recorded.Ten patients with left breast cancer who underwent breast conserv-ing surgery were selected for whole breast target delineation and breast gland target delineation,and the dosimetric param-eters of the two target delineation methods were compared.Result MRI examination showed that the breast cancer le-sions of 149 patients were located in the breast gland or the edge,and no breast cancer lesions occurred independently in the adipose tissues outside of the breast gland.The radiation volume,mean cardiac dose,and the left lung V20 obtained by breast gland target delineation were significantly lower than those by whole breast target delineation,and the differences were statistically significant(P<0.01).Conclusion In the whole-breast prophylactic irradiation of patients after breast conserving surgery,except for the need to expand the primary site to reduce the risk of recurrence,the target delineation should be limited to the residual breast glands visible on imaging,without covering the whole breast tissues,so as to re-duce the volume of whole breast irradiation and the dose of lung and heart irradiation,which is beneficial to the long-term survival of some breast cancer patients.
breast cancerMRI examinationbreast conserving surgerytarget delineation
NETL
NSTL
万方数据
维普
