摘要
目的 探讨手术室优质干预在早期食管癌根治术患者中的应用效果.方法 依据干预方式的不同将102例早期食管癌根治术患者分为对照组(n=51)和观察组(n=51),对照组患者给予常规干预,观察组患者在对照组的基础上给予手术室优质干预.比较两组患者的手术相关指标、应激反应指标[收缩压、舒张压、心率、动脉血氧饱和度(SaO2)]、心理状态[抑郁自评量表(SDS)、焦虑自评量表(SAS)]和生活质量[欧洲癌症研究与治疗组织生命质量测定量表(EORTC QLQ-C30)].结果 观察组患者术后清醒时间、拔管时间均明显短于对照组,差异均有统计学意义(P﹤0.01).术后,两组患者收缩压、舒张压、心率和SaO2均高于本组术前,观察组患者收缩压、舒张压、心率均低于对照组,差异均有统计学意义(P﹤0.05);术后,两组患者SaO2比较,差异无统计学意义(P﹥0.05).干预后,两组患者SDS、SAS评分均低于本组干预前,EORTC QLQ-C30量表各维度评分均高于本组干预前,观察组患者SDS、SAS评分均低于对照组,EORTC QLQ-C30量表各维度评分均高于对照组,差异均有统计学意义(P﹤0.05).结论 手术室优质干预应用于早期食管癌患者,有利于减轻手术应激反应,改善患者的不良心理状态,提高生活质量.
Abstract
Objective To explore the application effect of high-quality intervention in operating room in patients with early esophageal cancer radical surgery.Method According to different intervention methods,102 patients with early esophageal cancer radical surgery were divided into control group(n=51)and observation group(n=51),the control group received routine intervention,the observation group received high-quality intervention in operating room on the ba-sis of the control group.The surgical related indicators,stress response indicators[systolic blood pressure,diastolic blood pressure,heart rate,arterial oxygen saturation(SaO2)],psychological status[self-rating depression scale(SDS),self-rating anxiety scale(SAS)],and quality of life[European Organization for Research and Treatment of Cancer quality of life questionnaire core 30(EORTC QLQ-C30)]were compared between the two groups.Result The postoperative awaken-ing time and extubation time of the observation group were significantly shorter than those of the control group,and the differences were statistically significant(P<0.01).After surgery,the systolic blood pressure,diastolic blood pressure,heart rate,and SaO2 of the two groups were higher than those before surgery,the systolic blood pressure,diastolic blood pressure,and heart rate of the observation group were lower than those of the control group,and the differences were sta-tistically significant(P<0.05).After surgery,there was no significant difference in SaO2 between the two groups(P>0.05).After intervention,the SDS and SAS scores of both groups were lower than those before intervention,and the scores of all dimensions of EORTC QLQ-C30 scale were higher than those before intervention,the SDS and SAS scores of the observation group were lower than those of the control group,and the scores of all dimensions of EORTC QLQ-C30 scale were higher than those of the control group,and the differences were statistically significant(P<0.05).Conclu-sion High-quality intervention in operating room can be applied to early esophageal cancer patients,which is beneficial for reducing surgical stress response,improving patients'adverse psychological status,and improving their quality of life.
基金项目
河南省医学科技攻关计划(联合共建)项目(LHGJ20190217)
NETL
NSTL
万方数据