Predictive value of Charlson comorbidity index for the prognosis of low rectal cancer patients undergoing radical surgery
Objective To explore the predictive value of Charlson comorbidity index(CCI)for the prognosis of low rectal cancer patients undergoing radical surgery.Method A total of 84 low rectal cancer patients who received radical surgery were divided into mild group(CCI score≤3 points,n=64)and severe group(CCI score≥4 points,n=20)accord-ing to different CCI scores.The clinical characteristics of the two groups were compared.Followed up for 6 months,the survival of the two groups were compared.The receiver operating characteristic(ROC)curve was drawn,the area under the curve(AUC)was calculated,and the predictive value of CCI score for the prognosis of low rectal cancer patients un-dergoing radical surgery was analyzed.Result There were significant differences in age,differentiation degree and TNM stage between mild group and severe group(P<0.05).The 6-month survival rate in the mild group was 87.50%,which was significantly higher than 65.00%in the severe group,and the difference was statistically significant(P<0.01).ROC curve showed that CCI score had high predictive value for the prognosis of low rectal cancer patients undergoing radical surgery,the AUC was 0.817(95%CI:0.702-0.933),the sensitivity was 83.33%,and the specificity was 66.67%.Conclusion CCI score has a high predictive value for the prognosis of low rectal cancer patients undergoing radical sur-gery,patients with CCI score≥4 points have lower survival rate,which should be paid more attention to clinically.
Charlson comorbidity indexlow rectal cancerradical surgeryprognosispredictive value
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