Objective To investigate the diagnostic value of white light endoscopy combined with narrow-band imag-ing(NBI)magnifying endoscopy in gastric cancer.Method A total of 119 suspected gastric cancer patients were select-ed,and all patients underwent white light endoscopy,NBI magnifying endoscopy and pathological examination.The Kap-pa test was used to evaluate the consistency between the results of white light endoscopy,NBI magnifying endoscopy sin-gle and combined examination and pathological examination in the diagnosis of gastric cancer.The receiver operating characteristic(ROC)curve was drawn,the area under the curve(AUC)was calculated,and the diagnostic value of white light endoscopy,NBI magnifying endoscopy single and combined examination in gastric cancer were analyzed.The im-age quality of white light endoscopy and NBI magnifying endoscopy were compared,and the characteristics of gastric cancer and gastric benign diseases under endoscopy were also compared.Result Pathological examination showed that among the 119 patients,57 patients were gastric cancer and 62 patients were gastric benign diseases.The results of white light endoscopy,NBI magnifying endoscopy single and combined examination in the diagnosis of gastric cancer had good consistency with pathological examination results(Kappa=0.645,0.731,0.781,P<0.05).The AUC of white light en-doscopy,NBI magnifying endoscopy single and combined examination in the diagnosis of gastric cancer were 0.821,0.890 and 0.896,respectively,all of which had moderate diagnostic value,the AUC of white light endoscopy and NBI magnifying endoscopy combined examination were the highest.The image quality scores of NBI magnifying endoscopy were significantly higher than those of white light endoscopy in lesion boundary,gastric mucosal surface morphology and microvascular conditions,and the differences were statistically significant(P<0.01).The combined examination of white light endoscopy and NBI magnifying endoscopy showed that the proportions of clear lesion boundaries,irregular mucosal microvessels,irregular surface glandular ducts,and widened glandular spacing in gastric cancer patients were significant-ly lower than those in patients with gastric benign diseases,and the differences were statistically significant(P<0.01).Conclusion The combined examination of white-light endoscopy and NBI magnifying endoscopy has good diagnostic value for gastric cancer,which can provide relatively clear images.Moreover,the typical manifestations of gastric can-cer can be seen under white-light endoscopy combined with NBI magnifying endoscopy,which can provide reference for clinical diagnosis.
gastric cancerwhite light endoscopenarrow-band imagingmagnifying endoscopediagnostic value
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