Objective To evaluate the diagnostic value of TruScreen(TS)in early cervical cancer.Method A total of 100 women who underwent TS examination,thin-prep cytology test(TCT),human papilloma virus(HPV)test and his-topathology examination were selected.The diagnostic value of TS in the early cervical cancer was analyzed with the pathological results as the gold standard.Result The accuracy of TS in the diagnosis of early cervical cancer was 84.00%,and the consistency Kappa value with pathological results was 0.75(P<0.01).The accuracy of TCT and HPV in diagnosing early cervical cancer were both 76.00%,which were lower than that of TS.The area under the curve(AUC)of TS,TCT and HPV in diagnosing early cervical cancer were 0.772,0.728 and 0.712,respectively,and the AUC of TS was larger than that of TCT and HPV.The sensitivity of TS for diagnosing low-grade squamous intraepithelial lesion(LSIL)was 77.78%,that for diagnosing high-grade squamous intraepithelial lesion(HSIL)was 87.50%.Conclusion TS has high accuracy and reliability in the diagnosis of early cervical cancer.This system can provide reliable early screening re-sults,help early detection of cervical lesions,improve the diagnostic accuracy of cervical cancer,and provide better treat-ment and management strategies for patients.
TruScreenscreening for two cancerscervical cancerdiagnosis
NETL
NSTL
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