基于患者主观整体评估的个体化营养干预在胃癌根治术后辅助化疗患者中的应用效果

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中文摘要：目的探讨基于患者主观整体评估(PG-SGA)的个体化营养干预在胃癌根治术后辅助化疗患者中的应用效果.方法根据干预方式的不同将108例胃癌根治术后辅助化疗患者分为对照组(n=48)和观察组(n=60),对照组患者接受常规干预,观察组患者在对照组患者的基础上接受基于PG-SGA的个体化营养干预,比较两组患者的营养指标[白蛋白(ALB)、前白蛋白(PAB)、总蛋白(TP)、预后营养指数(PNI)]、免疫功能指标(CD3+、CD4+、CD4+/CD8+)、生活质量[欧洲癌症研究与治疗组织生命质量测定量表(EORTC QLQ-C30)]及满意情况.结果干预后,两组患者ALB、PAB、TP、PNI、CD3+、CD4+、CD4+/CD8+及EORTC QLQ-C30各维度评分均高于本组干预前,观察组患者ALB、PAB、TP、PNI、CD3+、CD4+、CD4+/CD8+、EORTC QLQ-C30各维度评分及总满意度均高于对照组,差异均有统计学意义(P＜0.05).结论基于PG-SGA的个体化营养干预应用于胃癌根治术后辅助化疗患者,可以改善患者的营养状态及免疫功能,提高患者的生活质量及满意度.

外文标题：Application effect of individualized nutrition intervention based on patient-generated subjective global assessment in patients with adjuvant chemotherapy after radical gastrectomy

外文摘要：Objective To investigate the application effect of individualized nutrition intervention based on patient-generated subjective global assessment(PG-SGA)in patients with adjuvant chemotherapy after radical gastrectomy.Method A total of 108 patients with adjuvant chemotherapy after radical gastrectomy were divided into control group(n=48)and observation group(n=60)according to different intervention methods.The control group received convention-al intervention,and the observation group received individualized nutrition intervention based on PG-SGA on the basis of the control group.The nutritional indexes[albumin(ALB),prealbumin(PAB),total protein(TP),prognostic nutritional index(PNI)],immune functions indexes(CD3+,CD4+,CD4+/CD8+),quality of life[European Organization for Research and Treatment of Cancer quality of life questionnaire core 30(EORTC QLQ-C30)]and satisfaction were compared be-tween the two groups.Result After intervention,the ALB,PAB,TP,PNI,CD3+,CD4+,CD4+/CD8+and EORTC QLQ-C30 scores in two groups were higher than those before intervention,the ALB,PAB,TP,PNI,CD3+,CD4+,CD4+/CD8+,EORTC QLQ-C30 scores and total satisfaction rate in observation group were higher than those in control group,and the differences were statistically significant(P＜0.05).Conclusion Individualized nutrition intervention based on PG-SGA is applied to patients with adjuvant chemotherapy after radical gastrectomy,which can improve the nutritional status and im-mune function,improve the quality of life and satisfaction of patients.

外文关键词：

radical gastrectomyadjuvant chemotherapypatient-generated subjective global assessmentindividual-ized nutrition intervention

作者：

田丹丹、王亚培、牟玉秀、吕宁

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作者单位：

郑州大学第一附属医院消化内科,郑州 450000

关键词：

胃癌根治术辅助化疗患者主观整体评估个体化营养干预

出版年：

2024

DOI：