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头颈部恶性肿瘤患者放疗后发生吞咽困难的影响因素分析

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目的 探讨头颈部恶性肿瘤(HNC)患者放疗后发生吞咽困难的影响因素.方法 根据放疗后是否发生吞咽困难将117例HNC患者分为观察组(n=48,发生吞咽困难)和对照组(n=69,未发生吞咽困难).比较两组患者的临床资料,采用二元Logistic回归模型分析HNC患者放疗后发生吞咽困难的影响因素.结果 两组患者的性别、吸烟史、肿瘤位置、放射剂量比较,差异均有统计学意义(P<0.05).多因素Logistic回归分析结果显示,男性、肿瘤位于颈部和耳鼻喉部、高放射剂量均是HNC患者放疗后发生吞咽困难的独立危险因素(P<0.05).结论 男性、肿瘤位于颈部和耳鼻喉部、高放射剂量均是HNC患者放疗后发生吞咽困难的独立危险因素,临床工作者应予以重视.
Analysis of influencing factors of dysphagia in patients with head and neck cancer after radiotherapy
Objective To explore the influencing factors of dysphagia in patients with head and neck cancer(HNC)after radiotherapy.Method A total of 117 patients with HNC were divided into observation group(n=48,dysphagia)and control group(n=69,no dysphagia)according to whether dysphagia occurred after radiotherapy.The clinical data of the two groups were compared,and the influencing factors of dysphagia in HNC patients after radiotherapy were ana-lyzed by binary Logistic regression model.Result There were significant differences in gender,smoking history,tumor location and radiation dose between the two groups(P<0.05).Multivariate Logistic regression analysis showed that male,tumor location in the neck,ear,nose and throat,and high radiation dose were independent risk factors for dyspha-gia in HNC patients after radiotherapy(P<0.05).Conclusion Male,tumor location in the neck,ear,nose and throat,and high radiation dose are independent risk factors for dysphagia in HNC patients after radiotherapy,clinical staff should pay attention to it.

head and neck cancerradiotherapydysphagiainfluencing factor

王建国、孟祥红、王勇、李红健

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滨州市第二人民医院放疗科,山东 滨州 256800

滨州市第二人民医院健康体检科,山东 滨州 256800

滨州市第二人民医院影像科,山东 滨州 256800

头颈部恶性肿瘤 放疗 吞咽困难 影响因素

2024

癌症进展
中国医学科学院,北京协和医学院

癌症进展

影响因子:1.004
ISSN:1672-1535
年,卷(期):2024.22(7)