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规范化疼痛干预在食管癌手术患者中的应用效果

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目的 探讨规范化疼痛干预在食管癌手术患者中的应用效果.方法 根据干预方式的不同将198例食管癌手术患者分为观察组(n=99,规范化疼痛干预)和对照组(n=99,常规疼痛干预).比较两组患者的自我感受负担[自我感受负担量表(SPBS)]、应激反应指标[C反应蛋白(CRP)、降钙素原(PCT)]、睡眠质量[匹兹堡睡眠质量指数(PSQI)]、疼痛程度[疼痛数字评分法(NRS)]、生活质量[癌症患者生命质量测定量表(FACT-G)]、住院时间及并发症发生情况.结果 干预后,两组患者SPBS各维度评分均低于本组干预前,观察组患者SPBS各维度评分均低于对照组,差异均有统计学意义(P﹤0.05).干预后,两组患者CRP、PCT水平均高于本组干预前,观察组患者CRP、PCT水平均低于对照组,差异均有统计学意义(P﹤0.05).干预后1、2周,两组患者PSQI评分均低于本组干预前,观察组患者PSQI评分均低于对照组,差异均有统计学意义(P﹤0.05).干预后1、2、4天,观察组患者NRS评分均低于本组干预前及对照组,差异均有统计学意义(P﹤0.05).干预后,两组患者FACT-G各维度评分及总分均高于本组干预前,观察组患者FACT-G各维度评分及总分均高于对照组,差异均有统计学意义(P﹤0.05).观察组患者的住院时间明显短于对照组(P﹤0.01).两组患者的并发症总发生率比较,差异无统计学意义(P﹥0.05).结论 规范化疼痛干预可降低食管癌手术患者的自我感受负担、应激反应指标及疼痛程度,提高睡眠质量和生活质量,还可缩短住院时间.
Application effect of standardized pain intervention in patients with esophageal cancer undergoing surgery
Objective To explore the application effect of standardized pain intervention in patients with esophageal cancer undergoing surgery.Method A total of 198 patients with esophageal cancer surgery were divided into observa-tion group(n=99,standardized pain intervention)and control group(n=99,conventional pain intervention)according to different intervention methods.The self-perceived burden[self-perceived burden scale(SPBS)],stress response indexes[C-reactive protein(CRP),procalcitonin(PCT)],sleep quality[Pittsburgh sleep quality index(PSQI)],pain degree[nu-merical rating scale(NRS)],quality of life[functional assessment of cancer therapy-general(FACT-G)],hospitalization time and complications were compared between the two groups.Result After intervention,the dimensional scores of SPBS in the two groups were lower than those before intervention,and the dimensional scores of SPBS in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).After inter-vention,the levels of CRP and PCT in the two groups were higher than those before intervention,and the levels of CRP and PCT in the observation group were lower than those in the control group,and the differences were statistically signifi-cant(P<0.05).One and two weeks after intervention,the PSQI scores in the two groups were lower than those before in-tervention,and the PSQI scores in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).One,two and four days after intervention,the NRS scores in the observation groups were lower than those before intervention and the control group,and the differences were statistically significant(P<0.05).After intervention,the dimensional scores and total scores of FACT-G in the two groups were higher than those before intervention,and the dimensional scores and total score of FACT-G in the observation group were higher than those in the control group,and the differences were statistically significant(P<0.05).The hospitalization time of the ob-servation group was significantly shorter than that of the control group(P<0.01).There was no significant difference in the total incidence of complications between the two groups(P>0.05).Conclusion Standardized pain intervention can reduce the self-perceived burden,stress response indexes and pain degree of esophageal cancer patients undergoing sur-gery,improve sleep quality and quality of life,and shorten hospitalization time.

standardized pain interventionesophageal cancerself-perceived burdenstress response indexsleep qualitypain degreequality of life

赵雅丽、张秀真、赵明明

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郑州大学第一附属医院肿瘤科一病区,郑州 4500000

规范化疼痛干预 食管癌 自我感受负担 应激反应指标 睡眠质量 疼痛程度 生活质量

2024

癌症进展
中国医学科学院,北京协和医学院

癌症进展

影响因子:1.004
ISSN:1672-1535
年,卷(期):2024.22(8)