MRI弥散加权成像与表观弥散系数对胃癌T分期的诊断价值
Diagnostic value of MRI diffusion weighted imaging and apparent diffusion coefficient in T staging of gastric cancer
张玮 1尉轶旻 2庞瑜丹 1陈宏3
作者信息
- 1. 复旦大学附属华山医院静安分院/上海市静安区中心医院 放射科,上海 2000400
- 2. 复旦大学附属华山医院静安分院/上海市静安区中心医院 核磁共振室,上海 2000400
- 3. 复旦大学附属华山医院静安分院/上海市静安区中心医院 普外科,上海 2000400
- 折叠
摘要
目的 探讨MRI弥散加权成像(DWI)和表观弥散系数(ADC)对胃癌T分期的诊断价值.方法 86例胃癌患者均进行MRI检查,以病理检查结果作为诊断金标准,分析DWI和ADC值对胃癌T分期的诊断价值.结果 ADC值诊断胃癌T分期的准确度为80.23%(69/86),Kappa值=0.704;DWI诊断胃癌T分期的准确度为81.40%(70/86),Kappa值为0.727;ADC值联合DWI诊断胃癌T分期的准确度为91.86%(79/86),高于ADC值和DWI单独检查,Kappa值为0.878.T1～2 期胃癌患者的ADC值为(1.17±0.23)×10-3 mm2/s,明显高于T3～4 期患者的(0.83±0.14)×10-3 mm2/s,差异有统计学意义(P﹤0.01).ADC值、DWI信号强度、f值联合检查对胃癌T分期的诊断价值优于三者单独检查.结论 ADC值联合DWI可为胃癌T分期的诊断提供一定临床依据,但ADC值因受多种因素影响,对胃癌T分期之间的区分具有一定局限性.
Abstract
Objective To investigate the diagnostic value of MRI diffusion weighted imaging(DWI)and apparent diffusion coefficient(ADC)in T staging of gastric cancer.Method MRI were performed in 86 patients with gastric cancer.The diagnostic value of DWI and ADC in T staging of gastric cancer were analyzed by pathological result as the diagnostic gold standard.Result The accuracy of ADC value in diagnosing T stage of gastric cancer was 80.23%(69/86),and Kappa value was 0.704.The accuracy of DWI in diagnosing T stage of gastric cancer was 81.40%(70/86),and Kappa value was 0.727.The accuracy of ADC value combined with DWI in diagnosing T stage of gastric cancer was 91.86%(79/86),higher than those of ADC value and DWI single examination,and Kappa=0.878.The ADC value in patients with stage T1-2 was(1.17±0.23)×10-3 mm2/s,which was significantly higher than(0.83±0.14)×10-3 mm2/s in patients with stage T3-4,and the difference was statistically significant(P<0.01).The combined examination of ADC val-ue,DWI signal strength and f value was better than the three tests single examination in diagnosing T stage of gastric can-cer.Conclusion ADC value combined with DWI can provide a certain clinical basis for the diagnosis of T stage of gas-tric cancer.However,ADC value is limited in distinguishing T stage of gastric cancer due to various factors.
关键词
胃癌/MRI/弥散加权成像/表观弥散系数/T分期Key words
gastric cancer/MRI/diffusion weighted imaging/apparent diffusion coefficient/T stage引用本文复制引用
出版年
2024
NETL
NSTL
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