首页|营养不良五阶梯治疗模式在腹腔镜胃癌根治术患者中的应用效果

营养不良五阶梯治疗模式在腹腔镜胃癌根治术患者中的应用效果

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目的 探讨营养不良五阶梯治疗模式在腹腔镜胃癌根治术患者中的应用效果.方法 采用抽签法将96例胃癌患者随机分为对照组和观察组,每组48例,对照组患者采取常规营养干预,观察组患者在对照组的基础上采取营养不良五阶梯治疗模式.比较两组患者的术后恢复指标、营养指标[血红蛋白(Hb)、前白蛋白(PAB)、白蛋白(ALB)、转铁蛋白(TRF)]、T淋巴细胞亚群(CD3+、CD4+、CD8+水平及CD4+/CD8+)以及并发症发生情况.结果 观察组患者首次下床活动时间、首次排气时间、肠鸣音恢复时间、首次进食时间、导管留置时间、住院时间均明显短于对照组,差异均有统计学意义(P<0.01).干预后,两组患者Hb、PAB、ALB、TRF水平均高于本组干预前,观察组患者Hb、PAB、ALB、TRF水平均高于对照组,差异均有统计学意义(P<0.05).干预后,两组患者CD3+、CD4+水平及CD4+/CD8+均高于本组干预前,CD8+水平均低于本组干预前,观察组患者CD3+、CD4+水平及CD4+/CD8+均高于对照组,CD8+水平低于对照组,差异均有统计学意义(P<0.05).观察组患者的并发症总发生率低于对照组(P<0.05).结论 营养不良五阶梯治疗模式应用于腹腔镜胃癌根治术患者,可促进患者术后恢复,改善患者的营养状态及免疫功能,降低并发症发生率.
Application effect of malnutrition five-step treatment model in patients undergoing laparoscopic radical gastrectomy
Objective To explore the application effect of malnutrition five-step treatment model in patients undergo-ing laparoscopic radical gastrectomy.Method A total of 96 patients with gastric cancer were randomly divided into con-trol group and observation group by drawing lots,with 48 cases in each group.Patients in the control group received con-ventional nutritional intervention,and patients in the observation group received malnutrition five-step treatment model on the basis of the control group.The postoperative recovery indexes,nutritional indexes[hemoglobin(Hb),prealbumin(PAB),albumin(ALB),transferrin(TRF)],T lymphocyte subsets(CD3+,CD4+,CD8+levels and CD4+/CD8+)and compli-cations of the two groups were compared.Result The first getting out of bed time,first exhaust time,bowel sound recov-ery time,first feeding time,catheter indwelling time and hospitalization time in the observation group were significantly shorter than those in the control group,and the differences were statistically significant(P<0.01).After intervention,the levels of Hb,PAB,ALB and TRF in both groups were higher than those before intervention,and the levels of Hb,PAB,ALB and TRF in the observation group were higher than those in the control group,and the differences were statistically significant(P<0.05).After intervention,the levels of CD3+,CD4+and CD4+/CD8+in both groups were higher than those before intervention,the levels of CD8+were lower than those before intervention,and the levels of CD3+,CD4+and CD4+/CD8+in the observation group were higher than those in the control group,and the level of CD8+was lower than that in the control group,and the differences were statistically significant(P<0.05).The total incidence of complications in the observation group was lower than that in the control group(P<0.05).Conclusion The application of malnutrition five-step treatment model in patients with laparoscopic radical gastrectomy can promote postoperative recovery,improve nutri-tional status and immune function of patients,and reduce the incidence of complications.

laparoscopic radical gastrectomymalnutrition five-step treatment modelpostoperative recovery indexnutritional indexT lymphocyte subset

赵勇、狄华明、舒鹏丽、马建文

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宁夏回族自治区人民医院普通外科,银川 750000

腹腔镜胃癌根治术 营养不良五阶梯治疗模式 术后恢复指标 营养指标 T淋巴细胞亚群

西北民族大学2019年中央高校基本科研业务费项目

31920190182

2024

癌症进展
中国医学科学院,北京协和医学院

癌症进展

影响因子:1.004
ISSN:1672-1535
年,卷(期):2024.22(9)