Effects of precision nutrition intervention on nutritional status and adverse reactions of prostate cancer patients undergoing postoperative chemotherapy
Objective To investigate the effects of precision nutrition intervention on nutritional status and adverse re-actions of prostate cancer(PCa)patients undergoing postoperative chemotherapy.Method A total of 90 postoperative chemotherapy patients with PCa were divided into control group(47 cases)and nutrition group(43 cases)according to different intervention programs.The control group received routine intervention,and the nutrition group received preci-sion nutrition intervention.The subjective nutritional status[patient generated subjective global assessment(PG-SGA)],objective nutritional status[transferrin(TRF),albumin(ALB),prealbumin(PAB)],incidence of chemotherapy adverse re-actions and quality of life[European Organization for Research and Treatment of Cancer quality of life questionnaire core 30(EORTC QLQ-C30)]were compared between the two groups.Result After intervention,the objective nutritional sta-tus of the nutritional group was significantly better than that of the control group,the difference was statistically signifi-cant(P＜0.01).After intervention,ALB,PAB and TRF in two groups were higher than those before intervention,and ALB,PAB and TRF in nutrition group were higher than those in control group,the differences were statistically signifi-cant(P＜0.05).After intervention,the EORTC QLQ-C30 scores in each dimension in both groups were higher than those before intervention,and the EORTC QLQ-C30 scores in each dimension in nutrition group were higher than those in con-trol group,the differences were statistically significant(P＜0.05).The total incidence of chemotherapy adverse reactions in nutrition group was lower than that in control group,and the difference was statistically significant(P＜0.05).Conclusion Precision nutrition intervention can effectively improve the nutritional status of patients with chemotherapy after PCa sur-gery,and reduce the adverse reactions of chemotherapy,which has certain advantages in improving the quality of life.
万方数据
维普
