首页|中西医联合干预在晚期肝癌患者中的应用效果

中西医联合干预在晚期肝癌患者中的应用效果

Application effect of combined intervention of traditional Chinese and Western medicine on patients with advanced liver cancer

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目的 探讨中西医联合干预在晚期肝癌患者中的应用效果.方法 依据治疗方法的不同将93例晚期肝癌患者分为常规组(n=45)和联合组(n=48),常规组患者给予常规干预,联合组患者给予中西医联合干预.比较两组患者心理状态[简明心境量表(POMS)]、负性情绪[焦虑自评量表(SAS)、抑郁自评量表(SDS)]、疼痛程度[视觉模拟评分法(VAS)评分]、生活质量[欧洲癌症研究与治疗组织生命质量测定量表(EORTC QLQ-C30)]和不良反应发生情况.结果 干预后和随访1个月时,两组患者VAS评分均低于本组干预前,联合组患者VAS评分均低于常规组,差异均有统计学意义(P<0.05).干预后,两组患者SAS、SDS评分以及POMS各维度评分和总分均低于本组干预前,联合组患者SAS、SDS评分以及POMS各维度评分和总分均低于常规组,差异均有统计学意义(P<0.05).干预后,两组患者EORTC QLQ-C30各维度评分均高于本组干预前,联合组患者EORTC QLQ-C30各维度评分均高于常规组,差异均有统计学意义(P<0.05).联合组患者的不良反应总发生率为4.17%,低于常规组患者的17.78%,1年生存率为97.92%,高于常规组患者的86.67%,差异均有统计学意义(P<0.05).结论 中西医联合干预可使晚期肝癌患者保持简明的心境,有助于缓解患者的负性情绪,减轻疼痛程度,提高生活质量,降低不良反应发生率.
Objective To explore the application effect of combined intervention of traditional Chinese and Western medicine on patients with advanced liver cancer.Method A total of 93 patients with advanced liver cancer were divided into conventional group(n=45)and combination group(n=48)based on different treatment methods.The conventional group received routine intervention,while the combination group received combined intervention of traditional Chinese and Western medicine.The psychological status[profile of mood state(POMS)],negative emotions[self-rating anxiety scale(SAS),self-rating depression scale(SDS)],pain level[visual analogue scale(VAS)score],quality of life[European Organization for Research and Treatment of Cancer quality of life questionnaire core 30(EORTC QLQ-C30)],and inci-dence of adverse reactions were compared between the two groups.Result After intervention and one month follow-up,the VAS scores of both groups were lower than those before intervention,and the VAS scores in the combination group were lower than those in the conventional group,and the differences were statistically significant(P<0.05).After interven-tion,the SAS,SDS scores,and the scores of all dimensions and total score of POMS scale of the two groups were lower than those before intervention,the SAS,SDS scores,and the scores of all dimensions and total score of POMS scale in the combination group were lower than those in the conventional group,and the differences were statistically significant(P<0.05).After intervention,the scores of all dimensions of EORTC QLQ-C30 in both groups were higher than those be-fore intervention,the scores of all dimensions of EORTC QLQ-C30 in the combination group were higher than those in the conventional group,and the differences were statistically significant(P<0.05).The total incidence of adverse reac-tions in the combination group was 4.17%,which was lower than 17.78%in the conventional group,and the 1-year sur-vival rate was 97.92%,which was higher than 86.67%in the conventional group,and the differences were statistically sig-nificant(P<0.05).Conclusion The combined intervention of traditional Chinese and Western medicine can help patients with advanced liver cancer maintain a concise mood,alleviate negative emotions and pain,improve quality of life,and re-duce the incidence of adverse reactions.

combined intervention of traditional Chinese and Western medicineadvanced liver cancerpain degreenegative emotionquality of life

李妍妍、王芳、栗瑞

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河南省中西医结合医院肿瘤血液科,郑州 450000

中西医联合干预 晚期肝癌 疼痛程度 负性情绪 生活质量

2024

癌症进展
中国医学科学院,北京协和医学院

癌症进展

影响因子:1.004
ISSN:1672-1535
年,卷(期):2024.22(11)
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