Objective To explore the relationship between frailty and postoperative complications in patients with spi-nal metastases.Method The medical records of 135 patients with spinal metastases who underwent surgery were collect-ed and divided into complication group(49 cases)and non-complication group(86 cases)according to the occurrence of postoperative complications.The clinical features of the two groups were compared.The metastatic spinal tumor frailty index(MSTFI)was used to evaluate the degree of frailty in patients with spinal metastases,and the incidence of complica-tions and length of hospital stay of patients with spinal metastases with different degrees of frailty were compared.Spear-man correlation analysis was used to analyze the correlation between frailty and postoperative complications in patients with spinal metastases.Logistic regression analysis was used to analyze the influencing factors of postoperative complica-tions in patients with spinal metastases.Receiver operating characteristic(ROC)curve and area under the curve(AUC)were used to analyze the value of frailty and American Society of Anesthesiologists(ASA)grade single and combined in predicting postoperative complications in patients with spinal metastases.Result There were significant differences in nutritional risk screening 2002(NRS 2002)score,ASA grade,frailty degree,activity of daily living(ADL)score,albu-min(ALB),postoperative hospital stay and total hospital stay between the complication group and the non-complication group(P<0.05).Among 135 patients with spinal metastases,25 patients had no frailty,55 patients had mild frailty,38 pa-tients had moderate frailty,and 17 patients had severe frailty.There was significant difference in the incidence of postop-erative venous thrombosis in patients with spinal metastases of different degrees of frailty(P<0.05).The total hospital stay of patients with severe frailty spinal metastases was longer than that of patients without frailty and patients with mild frailty,and the differences were statistically significant(P<0.05).Correlation analysis showed that frailty was positively correlated with postoperative complications in patients with spinal metastases(r=0.357,P<0.01).Logistic regression anal-ysis showed that severe frailty was an independent influencing factor for postoperative complications of patients with spi-nal metastases(P<0.05).The AUC of frailty for predicting postoperative complications of patients with spinal metastases was 0.703(95%CI:0.611-0.796).The AUC of ASA grade for predicting postoperative complications of patients with spi-nal metastases was 0.575(95%CI:0.476-0.674).The AUC of frailty combined ASA grade for predicting postoperative complications of patients with spinal metastases was 0.713(95%CI:0.622-0.805).Conclusion The incidence of frailty in patients with spinal metastases is high,and severe frailty is an independent influencing factor for postoperative compli-cations of patients with spinal metastases,and frailty has a certain predictive value for postoperative complications of pa-tients with spinal metastases.
frailtyspinal metastasespostoperative complicationpredictive value
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NSTL
万方数据
