综合干预对年轻卵巢癌术后腹腔灌注化疗患者应对方式及生活质量的影响
Effect of comprehensive intervention on coping style and quality of life of young ovarian cancer patients undergoing postoperative intraperitoneal perfusion chemotherapy
马润红 1李晓柳 1赵丹 1刘攀攀 1冯宪凌1
作者信息
- 1. 河南省人民医院妇科,河南省护理医学重点实验室,郑州大学人民医院,郑州 4500000
- 折叠
摘要
目的 探讨综合干预对年轻卵巢癌术后腹腔灌注化疗患者应对方式及生活质量的影响.方法 依据干预方式的不同将78例年轻卵巢癌术后腹腔灌注化疗患者分为常规组(n=37)和观察组(n=41),常规组患者采取常规干预,观察组患者采取综合干预.比较两组患者的心理状态[抑郁自评量表(SDS)、焦虑自评量表(SAS)]、应对方式[医学应对方式问卷(MCMQ)]、生活质量[欧洲癌症研究与治疗组织生命质量测定量表(EORTC QLQ-C30)]及不良反应发生情况.结果 干预后,两组患者SDS、SAS评分均低于本组干预前,观察组患者SDS、SAS评分均低于常规组,差异均有统计学意义(P﹤0.05).干预后,两组患者面对评分均高于本组干预前,回避、屈服评分均低于本组干预前,观察组患者面对评分高于常规组,回避、屈服评分均低于常规组,差异均有统计学意义(P﹤0.05).干预后,两组患者EORTC QLQ-C30各维度评分均高于本组干预前,观察组患者EORTC QLQ-C30各维度评分均高于常规组,差异均有统计学意义(P﹤0.05).观察组患者的不良反应总发生率为14.63%,明显低于常规组的54.05%,差异有统计学意义(P﹤0.01).结论 综合干预可改善年轻卵巢癌术后腹腔灌注化疗患者的负性情绪,提高积极应对水平和生活质量,降低不良反应发生率.
Abstract
Objective To explore the effect of comprehensive intervention on coping style and quality of life of young ovarian cancer patients undergoing postoperative intraperitoneal perfusion chemotherapy.Method A total of 78 young ovarian cancer patients undergoing postoperative intraperitoneal perfusion chemotherapy were divided into conven-tional group(n=37)and observation group(n=41)based on different intervention methods.The conventional group re-ceived routine intervention,while the observation group received comprehensive intervention.The psychological status[self-rating depression scale(SDS),self-rating anxiety scale(SAS)],coping style[medical coping mode questionnaire(MCMQ)],quality of life[European Organization for Research and Treatment of Cancer quality of life questionnaire core 30(EORTC QLQ-C30)],and incidence of adverse reactions were compared between the two groups.Result After inter-vention,the SDS and SAS scores of both groups were lower than those before intervention,the SDS and SAS scores of the observation group were lower than those of the conventional group,and the differences were statistically significant(P<0.05).After intervention,the confrontation scores of both groups were higher than those before intervention,the avoidance and surrender scores of both groups were lower than those before intervention,the confrontation score of the observation group was higher that of the conventional group,and the avoidance and surrender scores of the observation group were lower than those of the conventional group,and the differences were statistically significant(P<0.05).After intervention,the scores of all dimensions of EORTC QLQ-C30 in both groups were higher than those before intervention,the scores of all dimensions of EORTC QLQ-C30 in the observation group were higher than those in the conventional group,and the differences were statistically significant(P<0.05).The total incidence of adverse reactions in the observa-tion group was 14.63%,which was lower than 54.05%in the conventional group,and the difference was statistically sig-nificant(P<0.01).Conclusion Comprehensive intervention can improve the negative emotions of young ovarian cancer patients undergoing postoperative intraperitoneal perfusion chemotherapy,improve their level of positive coping and qual-ity of life,reduce the incidence of adverse reactions.
关键词
卵巢癌/腹腔灌注化疗/综合干预/生活质量/不良反应Key words
ovarian cancer/intraperitoneal perfusion chemotherapy/comprehensive intervention/quality of life/ad-verse reaction引用本文复制引用
出版年
2024
NETL
NSTL
万方数据