Efficacy of pulmonary lobectomy,pulmonary wedge resection and pulmonary segmentectomy in treatment of elderly patients with stage Ⅰ non-small cell lung cancer and the effect on prognosis
Efficacy of pulmonary lobectomy,pulmonary wedge resection and pulmonary segmentectomy in treatment of elderly patients with stage Ⅰ non-small cell lung cancer and the effect on prognosis
Objective To compare the efficacy of pulmonary lobectomy,pulmonary wedge resection and pulmonary segmentectomy in the treatment of elderly patients with stage Ⅰ non-small cell lung cancer(NSCLC)and the effect on prognosis.Method A total of 105 elderly patients with stage I NSCLC were divided into group A(pulmonary lobecto-my,n=36),group B(pulmonary wedge resection,n=32)and group C(pulmonary segmentectomy,n=37)according to dif-ferent surgical methods.Perioperative indexes,perioperative complications,pulmonary function indexes[forced vital ca-pacity(FVC),diffusion capacity of carbon monoxide of lung(DLCO),maximal voluntary ventilation(MVV)],postopera-tive follow-up(recurrence,distant metastasis,and death)of the 3 groups were compared.Result The operative time,postoperative drainage time and postoperative hospitalization time of group B were shorter than those of group A and group C,and the operative time of group C was shorter than those of group A,the differences were statistically significant(P<0.05).There was no significant difference in the total incidence of perioperative complications among 3 groups(P>0.05).Six months after operation,FVC and DLCO in group A were lower than those before operation,FVC,DLCO and MVV in group B and group C were higher than those in group A,the differences were statistically significant(P<0.05).After 1 year follow-up,there were no statistical significances in recurrence and distant metastasis among the 3 groups(P>0.05),and no death occurred in the 3 groups.Conclusion Sublobectomy can promote postoperative recovery and pulmo-nary function improvement in elderly patients with stage I NSCLC.It is recommended to choose the operation according to the actual situation of patients.
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