Objective To explore the clinical manifestations and prognostic factors analysis of multiple myeloma(MM)patients with renal injury.Method The medical records of MM patients complicated with renal injury were col-lected and the clinical manifestations of MM patients complicated with renal injury were analyzed.All patients were fol-lowed up for 1 year and divided into good prognosis(n=90)and poor prognosis(n=31)according to the prognosis,and the influencing factors of prognosis of MM complicated with renal injury patients were analyzed by Logistic regression model.Result The most common first symptom of MM complicated with renal injury patients was anemia(72.73％),followed by infection(44.63％),edema of the face and lower limbs(42.98％),and elevated blood pressure(33.88％).The most common pathological type of MM complicated with renal injury patients was tubular nephropathy(48.76％),fol-lowed by amyloidosis(25.62％).There were statistically significant differences in uric acid,β2-microglobulin and magne-sium levels between MM complicated with renal injury patients with poor prognosis and good prognosis(P＜0.05).Multi-variate Logistic regression analysis showed that uric acid,β2-microglobulin and blood magnesium were influencing fac-tors of prognosis of MM complicated with renal injury patients(P＜0.05).Conclusion Anemia,infection,edema of the face and lower limbs,elevated blood pressure,tubular nephropathy and amyloidosis are common clinical manifestations in MM complicated with renal injury patients.The uric acid,β2-microglobulin and blood magnesium are influencing fac-tors of prognosis of MM complicated with renal injury patients.
维普
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