Objective To study the differential diagnostic value of energy spectral CT examination in benign and ma-lignant lung tumors.Method A total of 156 patients with lung tumors underwent conventional multi-slice spiral CT and energy spectrum CT examinations.According to the pathological examination results,they were divided into benign group(n=53)and malignant group(n=103).The conventional CT value and energy spectrum CT quantitative parameters[slope K,normalized iodine concentration(NIC)in arterial phase and venous phase]were compared between the two groups.The receiver operating characteristic(ROC)curve was drawn,the area under the curve(AUC)was calculated,and the differential diagnostic value of conventional CT and energy spectrum CT examinations in benign and malignant lung tumors were evaluated.Result The conventional CT value,NIC in arterial phase,NIC in venous phase and slope K in the malignant group were significantly higher than those in the benign group,the differences were statistically signifi-cant(P＜0.01).The diagnostic value of energy spectrum CT examination for lung malignant tumors was relatively high(AUC=0.910,95％CI:0.865-0.955),which was superior to conventional CT examination(AUC=0.759).Conventional CT value≥26.77 HU was the indication of malignancy in the diagnosis of pulmonary malignant tumors by conventional CT examination,and the diagnostic value was moderate.The AUC of energy spectral CT parameter NIC in venous phase in diagnosis of lung malignant tumors was 0.868,and the diagnostic value was moderate.Conclusion Compared with conventional CT examination,energy spectrum CT examination has high differential diagnostic value for benign and ma-lignant lung tumors,and the diagnostic value of NIC in venous phase is higher than other energy spectral CT parameters,which can provide reference for the clinical examination of benign and malignant lung tumors.
energy spectrum CTlung tumornormalized iodine concentration
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