首页|地佐辛注射液对胸腔镜肺占位性病变手术患者的术后镇痛效果

地佐辛注射液对胸腔镜肺占位性病变手术患者的术后镇痛效果

Postoperative analgesic effect of dezocine injection on patients with thoracoscopic lung space-occupying lesion surgery

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目的 探讨地佐辛注射液对胸腔镜肺占位性病变手术患者的术后镇痛效果.方法 将60例行胸腔镜肺占位性病变手术患者采用随机数字表法分为地佐辛组(30例)和构橼酸舒芬太尼组(30例).地佐辛组应用地佐辛注射液术后镇痛方案,枸橼酸舒芬太尼组应用构橼酸舒芬太尼注射液术后镇痛方案.比较两组患者的应激反应指标[心率(HR)、平均动脉压(MAP)]、疼痛程度[视觉模拟评分法(VAS)评分]、镇静效果(Ramsay镇静量表评分)及不良反应发生情况.结果 术后1、6、12、24h,地佐辛组患者HR、MAP和VAS评分均低于构橼酸舒芬太尼组,差异均有统计学意义(P<0.05).术后1、6、12 h,地佐辛组患者Ramsay镇静量表评分均低于构橼酸舒芬太尼组,差异均有统计学意义(P<0.05).两组患者不良反应总发生率比较,差异无统计学意义(P>0.05).结论 地佐辛注射液在胸腔镜肺占位性病变手术患者术后镇痛中的应用效果较好,可快速缓解术后疼痛,减轻术后应激反应,且安全可靠,具有较高的临床应用价值.
Objective To investigate the postoperative analgesic effect of dezocine injection on patients with thoraco-scopic lung space-occupying lesions surgery.Method A total of 60 patients who underwent thoracoscopic surgery for lung space-occupying lesions were divided into dezocine group(30 cases)and sufentanil citrate group(30 cases)by ran-dom number table method.Dezocine group was given the postoperative analgesia program of dezocine injection,and suf-entanil citrate group was given the postoperative analgesia program of sufentanil citrate injection.Stress response indica-tors[heart rate(HR),mean arterial pressure(MAP)],pain degree[visual analogue scale(VAS)score],sedation effect(Ramsay sedation scale score)and the occurrence of adverse reactions were compared between the two groups.Result At 1,6,12,24 h after surgery,the HR,MAP and the scores of VAS in dezocine group were lower than those in sufentanil citrate group,the differences were statistically significant(P<0.05).At 1,6,12 h after surgery,the scores of Ramsay seda-tion scale of dezocine group were lower than those of sufentanil citrate group,and the differences were statistically signifi-cant(P<0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(P>0.05).Conclusion Dezocine injection has a good effect on postoperative analgesia in patients with thoracoscopic lung space-occupying lesions surgery,which can quickly relieve postoperative pain and reduce postoperative stress response.It is safe and reliable,and has high clinical application value.

dezocine injectionsufentanil citrate injectionthoracoscopic lung space-occupying lesion surgerypost-operative analgesia

张文、吴魏、罗冬冬

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吉安市中心人民医院(上海市东方医院吉安医院)重症医学科,江西 吉安 343000

地佐辛注射液 枸橼酸舒芬太尼注射液 胸腔镜肺占位性病变手术 术后镇痛

江西省卫生健康委科技计划项目

202140982

2024

癌症进展
中国医学科学院,北京协和医学院

癌症进展

影响因子:1.004
ISSN:1672-1535
年,卷(期):2024.22(17)