Objective To explore the clinical efficacy of stereotactic minimally invasive surgery in cerebral glioma patients and its influence on neurological function.Method According to different surgical methods,80 patients with ce-rebral glioma were divided into minimally invasive group(n=10,stereotactic minimally invasive surgery)and control group(n=70,traditional craniotomy).The clinical efficacy,neurological function[Glasgow coma scale(GCS),National Institutes of Health stroke scale(NIHSS)],neuropeptide indexes[oxytocin(OT),arginine vasopressin(AVP),β-endor-phin(β-EP)]and complications were compared between the two groups.Result The total response rate in minimally in-vasive group was higher than that in control group,and the difference was statistically significant(P<0.05).Three months after surgery,the GCS scores in both groups were higher than those before surgery,and the NIHSS scores were lower than those before surgery,the GCS score in minimally invasive group was higher than that in control group,and the NI-HSS score was lower than that in control group,and the differences were statistically significant(P<0.05).Three months after surgery,the levels of OT,AVP and β-EP in both groups were lower than those before surgery,and the levels of OT,AVP and β-EP in minimally invasive group were higher than those in control group,and the differences were statistically significant(P<0.05).There was no significant difference in the total incidence of complications between the two groups(P>0.05).Conclusion Compared with traditional craniotomy,stereotactic minimally invasive surgery has a significant clinical effect in the treatment of cerebral glioma,and can protect the neurological function of patients.
cerebral gliomastereotactic minimally invasive surgerytraditional craniotomyneurological function
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