Objective To investigate the typing of human papilloma virus(HPV)and its relationship with clinical characteristics and prognosis in patients with endogenous cervical cancer(ECCA).Method A total of 120 patients with ECCA were selected as the study group,and 90 patients with exceptional cervical cancer were selected as the control group.All patients had HPV infection,HPV typing was detected at admission.The HPV typing of the two groups was compared,and the relationship between HPV typing and clinical characteristics of ECCA patients was analyzed.After 12 months of follow-up,Cox regression model was used to analyze the prognostic factors of ECCA patients.Result The incidence rate of HPV31/51 infection in the study group was significantly higher than that in the control group,and the incidence rate of HPV16/18 infection was significantly lower than that in the control group,the differences were statis-tically significant(P<0.01).There were significant differences in HPV typing among ECCA patients with different clini-cal stages and lymph node metastasis(P<0.05).The results of multivariate analysis showed that HPV type 31/51 and lymph node metastasis were independent risk factors for prognosis in ECCA patients(P<0.01).Conclusion Most of the HPV typing in ECCA patients are 31/51,and HPV31/51 infection and lymph node metastasis are independent risk factors for prognosis of ECCA patients.
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