Objective To explore the differential diagnostic value of shear wave elastography(SWE),ultrasound-guided biopsy combined examination for benign and malignant thyroid tumors.Method A total of 57 patients with thy-roid tumors were selected,all of whom underwent ultrasound-guided biopsy and SWE examination.The results of surgi-cal pathological examination was used as the gold standard,and the differential diagnostic value of SWE,ultrasound-guid-ed biopsy single and combined examinations for benign and malignant thyroid tumors were evaluated.The consistency between the results of SWE,ultrasound-guided biopsy single and combined examinations for differential diagnosis of be-nign and malignant thyroid tumors and pathological examination results was determined by Kappa test.Result The post-operative pathological examination results showed that among the 57 patients with thyroid tumors,20 cases were benign and 37 cases were malignant.The sensitivity,specificity,accuracy,positive predictive value,and negative predictive val-ue of SWE single examination in diagnosing thyroid malignant tumors were 67.57%,90.00%,75.44%,92.59%,and 60.00%,respectively,and the consistency with pathological examination results was moderate(Kappa=0.516).The sensi-tivity,specificity,accuracy,positive predictive value,and negative predictive value of ultrasound-guided biopsy single ex-amination in diagnosing thyroid malignant tumors were 72.97%,85.00%,77.19%,90.00%,and 62.96%,respectively,and the consistency with pathological examination results was moderate(Kappa=0.537).The sensitivity,specificity,accuracy,positive predictive value,and negative predictive value of SWE and ultrasound-guided biopsy combined examination in diagnosing thyroid malignant tumors were 86.49%,80.00%,84.21%,88.89%,and 76.19%,respectively,and the consis-tency with pathological examination results was high(Kappa=0.657).The sensitivity,accuracy and negative predictive value of SWE,ultrasound-guided biopsy combined examination in diagnosing thyroid malignant tumors were higher than those of the single examination.Conclusion SWE,ultrasound-guided biopsy combined examination has a high value in the differential diagnosis of benign and malignant thyroid tumors,and the consistency with pathological examination re-sults is high.
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