癌症进展2024,Vol.22Issue(22) :2503-2505,2512.DOI:10.11877/j.issn.1672-1535.2024.22.22.17

全膝关节置换术治疗膝关节周围恶性骨肿瘤患者的疗效及影响因素分析

Analysis of efficacy of total knee arthroplasty in patients with malignant bone tumor around knee joint and its influencing factor

刘婷 刘军
癌症进展2024,Vol.22Issue(22) :2503-2505,2512.DOI:10.11877/j.issn.1672-1535.2024.22.22.17

全膝关节置换术治疗膝关节周围恶性骨肿瘤患者的疗效及影响因素分析

Analysis of efficacy of total knee arthroplasty in patients with malignant bone tumor around knee joint and its influencing factor

刘婷 1刘军1
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作者信息

  • 1. 天津市天津医院康复科,天津 300000
  • 折叠

摘要

目的 探讨全膝关节置换术(TKA)治疗膝关节周围恶性骨肿瘤患者的疗效及影响因素.方法 选取48例膝关节周围恶性骨肿瘤患者,入院后均行TKA手术治疗.评价患者的临床疗效,并分为有效组和无效组.采用美国膝关节协会评分(AKS)评价手术前后两组患者的膝关节功能,分析TKA治疗膝关节周围恶性骨肿瘤患者疗效的影响因素.结果 TKA治疗膝关节周围恶性骨肿瘤的总有效率为75.00%,其中,有效组36例,无效组12例.手术后,两组患者AKS评分均升高,且有效组患者AKS评分高于无效组,差异均有统计学意义(P﹤0.05).多因素Logistic回归分析结果显示,置入假体类型为后交叉韧带保留型(CR)患者临床疗效较好(P﹤0.05).结论 TKA手术可改善膝关节周围恶性骨肿瘤患者的膝关节功能,其临床疗效与置入假体类型有关.

Abstract

Objective To investigate the efficacy of total knee arthroplasty(TKA)in patients with malignant bone tu-mor around knee joint and its influencing factors.Method A total of 48 patients with malignant bone tumor around knee joint were selected and treated with TKA after admission.The clinical efficacy was evaluated and patients were divided into effective group and ineffective group.The American Knee Association score(AKS)was used to evaluate the knee joint function of the two groups before and after operation,and the influencing factors of TKA treatment efficacy in malig-nant bone tumors around the knee joint were analyzed.Result The total effective rate of TKA in the treatment of malig-nant bone tumors around the knee joint was 75.00%,including 36 cases in effective group and 12 cases in ineffective group.After operation,the AKS scores were increased in both groups,and the AKS score in effective group was higher than that in ineffective group,the differences were statistically significant(P<0.05).Multivariate Logistic regression anal-ysis showed that patients with cruciate retention(CR)implant had better clinical efficacy(P<0.05).Conclusion TKA can improve the knee joint function of patients with malignant bone tumors around knee joint,and its clinical efficacy is related to the type of implanted prosthesis.

关键词

恶性骨肿瘤/全膝关节置换术/膝关节功能/疗效

Key words

malignant bone tumor/total knee arthroplasty/knee joint function/curative effect

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出版年

2024
癌症进展
中国医学科学院,北京协和医学院

癌症进展

影响因子:1.004
ISSN:1672-1535
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