Analysis of the accuracy of preoperative ultrasound examination,fine-needle aspiration biopsy,and intraoperative frozen section examination in diagnosing thyroid cancer and its influencing factors
Objective To explore the accuracy of preoperative ultrasound examination,fine-needle aspiration biopsy,and intraoperative frozen section examination in diagnosing thyroid cancer,and to analyze the influencing factors of accu-racy.Method A total of 103 patients with thyroid disease were selected,and underwent preoperative ultrasound exami-nation,preoperative fine-needle aspiration biopsy,intraoperative frozen section,and postoperative pathological examina-tion.The diagnostic accuracy of preoperative ultrasound examination,preoperative fine-needle aspiration biopsy,and in-traoperative frozen section for thyroid cancer was compared.The influencing factors of the accuracy of preoperative ultra-sound examination,preoperative fine-needle aspiration biopsy,and intraoperative frozen section examination in diagnos-ing thyroid cancer were analyzed by multivariate Logistic regression.Result Postoperative pathological examination showed that among 103 patients with thyroid disease were thyroid cancer.The accuracy of preoperative ultrasound exami-nation,preoperative fine-needle aspiration biopsy,and intraoperative frozen section in diagnosing thyroid cancer were 81.55%(84/103),94.17%(97/103),and 97.09%(100/103),respectively.Multivariate Logistic regression showed that tu-mor diameter≤1 cm was independent risk factor for the accuracy of preoperative ultrasound examination in diagnosis of thyroid cancer(P<0.05),whether to refer the ultrasound parameters and diagnosis was not influencing factor for the accu-racy of preoperative fine-needle aspiration biopsy in diagnosis of thyroid cancer(P>0.05),the obvious accompanying in-flammation was independent risk factor for the accuracy of preoperative fine-needle aspiration biopsy in diagnosis of thy-roid cancer(P<0.05).Conclusion The accuracy of preoperative-fine needle aspiration biopsy and intraoperative frozen section examination in diagnosing thyroid cancer are higher than that of preoperative ultrasound examination,the tumor diameter≤1 cm is independent risk factor for the accuracy of preoperative ultrasound examination,and the obvious ac-companying inflammation is independent risk factor for the accuracy of preoperative fine-needle aspiration thyroid cancer.