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老年胆管癌患者术后感染性并发症发生的影响因素及干预对策

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目的 探讨老年胆管癌患者术后感染性并发症发生的影响因素及干预对策.方法 根据术后是否发生感染性并发症将84例行手术治疗的老年胆管癌患者分为感染组(n=29)和未感染组(n=55).收集并比较两组患者的临床资料,采用Logistic回归模型分析老年胆管癌患者术后感染性并发症发生的影响因素.结果 感染组与未感染组患者的病灶直径、手术方式、手术时间、术后住院时间、抗生素使用时间、尿管留置时间、胆道梗阻情况、术后胆漏情况比较,差异均有统计学意义(P﹤0.05).多因素Logistic回归分析结果显示,手术时间较长、尿管留置时间﹥5天、胆道梗阻、术后胆漏均是老年胆管癌患者术后感染性并发症发生的独立危险因素(P﹤0.05).结论 手术时间较长、尿管留置时间﹥5天、胆道梗阻、术后胆漏均是老年胆管癌患者术后感染性并发症发生的独立危险因素.临床应综合考虑这些因素,采取多层次的预防和干预措施,以降低术后感染发生率并改善患者预后.
Influencing factors and intervention strategies of postoperative infectious complications in elderly patients with cholangiocarcinoma
Objective To investigate the influencing factors and intervention strategies of postoperative infectious complications in elderly patients with cholangiocarcinoma.Method A total of 84 elderly patients with cholangiocarcino-ma who underwent surgery were divided into infected group(n=29)and non-infected group(n=55)according to the oc-currence of postoperative infectious complications.The clinical data of the two groups were collected and compared,and the influencing factors of postoperative infectious complications in elderly patients with cholangiocarcinoma were ana-lyzed by Logistic regression model.Result There were statistically significant differences in lesion diameter,operation method,operation time,postoperative hospital stay,antibiotic use time,urinary catheter indwelling time,biliary obstruc-tion and postoperative bile leakage between infected group and non-infected group(P<0.05).Multivariate Logistic regres-sion analysis showed that longer operation time,urinary catheter indwelling time>5 days,biliary obstruction and postoper-ative bile leakage were independent risk factors for postoperative infectious complications in elderly patients with cholan-giocarcinoma(P<0.05).Conclusion Longer operation time,urinary catheter indwelling time>5 days,biliary obstruction and postoperative bile leakage were independent risk factors for postoperative infectious complications in elderly patients with cholangiocarcinoma.In order to reduce the incidence of postoperative infection and improve the prognosis of pa-tients,multi-level prevention and intervention measures should be taken comprehensively considering these factors.

elderlycholangiocarcinomapostoperative infectious complicationintervention strategy

李莉、李馨、仝永方、王东彩

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郑州大学第一附属医院肝胆胰外科,郑州 450001

老年 胆管癌 术后感染性并发症 干预对策

2024

癌症进展
中国医学科学院,北京协和医学院

癌症进展

影响因子:1.004
ISSN:1672-1535
年,卷(期):2024.22(23)