急诊经导管动脉栓塞化疗治疗肝癌自发性破裂出血患者的近期预后影响因素分析
Influencing factors of short-term prognosis of patients with spontaneous rupture hemorrhage of liver cancer treated by emergency transcatheter arterial chemoembolization
杨锴 1林建平 1胡云1
作者信息
- 1. 新余市人民医院创伤急救中心,江西 新余 338000
- 折叠
摘要
目的 探讨急诊经导管动脉栓塞化疗(TACE)治疗肝癌自发性破裂出血患者的近期预后影响因素.方法 选取55例急诊收治的肝癌自发性破裂出血患者,所有患者均实施TACE治疗,根据治疗后3个月生存情况分为预后良好组(n=39)和预后不良组(n=16).采用多因素Logistic回归分析模型分析急诊TACE治疗肝癌自发性破裂出血患者近期预后的影响因素.结果 两组患者年龄、肿瘤直径、Child-Pugh分级、TNM分期、白细胞计数(WBC)、血红蛋白(Hb)、凝血酶原时间(PT)、甲胎蛋白(AFP)比较,差异均有统计学意义(P﹤0.05).多因素Logistic回归分析结果显示,肿瘤直径、Child-Pugh分级、Hb水平均为急诊TACE治疗肝癌自发性破裂出血患者近期预后的独立影响因素(P﹤0.01).结论 急诊TACE治疗肝癌自发性破裂出血患者近期预后与肿瘤直径、Child-Pugh分级、Hb水平密切相关.
Abstract
Objective To investigate the influencing factors of short-term prognosis of patients with spontaneous rup-ture hemorrhage of liver cancer treated by emergency transcatheter arterial chemoembolization(TACE).Method A total of 55 patients with spontaneous rupture hemorrhage of liver cancer admitted to the emergency department were selected,all patients were treated with TACE,and were divided into good prognosis group(n=39)and poor prognosis group(n=16)according to survival after 3 months of treatment.Multivariate Logistic regression analysis model was used to analyze the influencing factors of the short-term prognosis of patients with spontaneous rupture hemorrhage of liver cancer treated by emergency TACE.Result There were significant differences in age,tumor diameter,Child-Pugh grade,TNM stage,white blood cell count(WBC),hemoglobin(Hb),prothrombin time(PT)and α-fetal protein(AFP)between the two groups(P<0.05).Multivariate Logistic regression analysis showed that tumor diameter,Child-Pugh grade and Hb level were independent influencing factors of the short-term prognosis of patients with spontaneous rupture hemorrhage of live cancer treated by emergency TACE(P<0.01).Conclusion The short-term prognosis of patients with spontaneous rup-ture hemorrhage of liver cancer treated by emergency TACE is closely related to tumor diameter,Child-Pugh grade and Hb level.
关键词
经导管动脉栓塞化疗/肝癌/自发性破裂出血/预后/影响因素Key words
transcatheter arterial chemoembolization/liver cancer/spontaneous rupture hemorrhage/prognosis/in-fluencing factor引用本文复制引用
出版年
2024
NETL
NSTL
万方数据