Construction and validation of a nomogram model for major cardiovascular adverse events in acute myocardial infarction patients within 2 years after percutaneous coronary intervention
Construction and validation of a nomogram model for major cardiovascular adverse events in acute myocardial infarction patients within 2 years after percutaneous coronary intervention
Objective:To study the risk factors of major adverse cardiovascular events in acute myocardial infarction ( AMI) patients within 2 years after percutaneous coronary intervention ( PCI),construct a nomogram model and verify it. Methods:The clinical data of 491 patients with AMI undergoing PCI were analyzed retrospectively. The patients were randomly divided into a modeling group of 345 cases and a validation group of 146 cases in a 7:3 ratio. The influencing factors of major adverse cardiovascular events in the modeling group within 2 years were analyzed by univariate and multivariate logistic regression analysis,and a nomogram model was constructed and verified. Results:Univariate and multivariate logistic regression analysis showed that age,fQRS wave,Gensini score and neutrophils/lymphocytes ratio ( NLR) were independent influencing factors of major adverse cardiovascular events in AMI patients within 2 years after PCI (P<0. 05 to P<0. 01). The nomogram was drawn,and the AUC of the modeling group was 0. 743,showing that the model had good discrimination,the H-L curve was well fitted (x2=3. 827,P=0. 922),and the AUC of the validation group was 0. 720,indicating that the model was accurate. Conclusions:The age,fQRS wave,Gensini score and NLR are independent risk factors for major adverse cardiovascular events in AMI patients within 2 years after PCI,and the nomogram model has a good predictive function.
维普
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