蚌埠医学院学报2024,Vol.49Issue(9) :1141-1144.DOI:10.13898/j.cnki.issn.1000-2200.2024.09.004

急性上消化道出血再出血的危险因素分析

Analysis of risk factors for rebleeding in acute upper gastrointestinal bleeding

李娟娟 闻静 张超 李晓玉
蚌埠医学院学报2024,Vol.49Issue(9) :1141-1144.DOI:10.13898/j.cnki.issn.1000-2200.2024.09.004

急性上消化道出血再出血的危险因素分析

Analysis of risk factors for rebleeding in acute upper gastrointestinal bleeding

李娟娟 1闻静 1张超 2李晓玉3
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作者信息

  • 1. 蚌埠医科大学第二附属医院消化内科,安徽 蚌埠233040
  • 2. 蚌埠医科大学第一附属医院 肿瘤外科,安徽 蚌埠233004
  • 3. 蚌埠医科大学第二附属医院全科医学科,安徽 蚌埠233040
  • 折叠

摘要

目的:探讨急性上消化道出血(AUGIB)病人再出血危险因素.方法:回顾性分析50例AUGIB病人的临床相关资料,按是否再出血分为再出血组和未再出血组,对2组病人临床资料进行分析,探讨发生再出血的危险因素.结果:AUGIB病人中再出血组12例(24%)、未再出血组38例(76%),男女比例为3.5︰1,消化性溃疡30例;2组呕血、中性分叶核比例、红细胞分布宽度、血小板、白蛋白、凝血酶原时间、活化部分凝血活酶时间、凝血酶时间、纤维蛋白原、血浆D-二聚体等差异均有统计学意义(P<0.05~P<0.01);logistic回归分析显示:D-Dimer(OR:0.994,95%CI:0.989~1.000)、血小板(OR:1.066,95%CI:0.994~1.144)是AUGIB病人发生再出血的独立危险因素.结论:AUGIB多见于男性,消化道性溃疡伴出血最为常见,血小板、血浆D-二聚体水平是发生再出血的独立危险因素.

Abstract

Objective:To explore the risk factors for rebleeding in patients with (AUGIB).Methods:A retrospective analysis was conducted on the clinical data of 50 patients with AUGIB,who were divided into a rebleeding group and a non-rebleeding group based on whether they experienced rebleeding.The clinical data of the two groups of patients were analyzed to explore the risk factors for rebleeding.Results:Among AUGIB patients,there were 12 cases (24%) in the rebleeding group and 38 cases (76%) in the non-rebleeding group,with a male to female ratio of 3.5︰1.There were 30 cases of peptic ulcer.There were statistically significant differences in vomiting blood,proportion of neutrophils,red blood cell distribution width,platelets,albumin,prothrombin time,activated partial thromboplastin time,thrombin time,fibrinogen,and plasma D-dimer between the two groups (P<0.05 to P<0.01).Logistic regression analysis showed that D-Dimer (OR:0.994,95%CI:0.989-1.000) and platelets (OR:1.066,95%CI:0.994-1.144) were independent risk factors for rebleeding in AUGIB patients.Conclusions:AUGIB is more common in males,and gastrointestinal ulcers with bleeding are the most common.Platelet and plasma D-dimer levels are independent risk factors for rebleeding.

关键词

急性上消化道出血/再出血/D-二聚体/血小板

Key words

acute upper gastrointestinal bleeding/rebleeding/D-Dimer/platelet

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基金项目

蚌埠医学院自然科学研究重点项目(2023byzd104)

出版年

2024
蚌埠医学院学报
蚌埠医学院

蚌埠医学院学报

CSTPCD
影响因子:0.917
ISSN:1000-2200
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