Objective:To explore the relationship between disease cognition,disease uncertainty,death anxiety and rehospitalization in patients with pulmonary heart disease(PHD).Methods:A total of 249 patients with PHD were selected.According to whether or not re-hospitalization,the patients were divided into re-hospitalization group(72 cases)and non-hospitalization group(177 cases).The patients were investigated by self-designed general information questionnaire,self-developed disease cognition scale,Mishel Uncertainty in Illness Scale(MUIS-A),and Chinses version of Templer's death anxiety scale(CT-DAS).Results:The total scores of disease cognition scale in the re-hospitalization group were lower than those in the non-hospitalization group(P<0.01),and the total scores and all dimensions scores of MUIS,CT-DAS were higher than those in the non-hospitalization group(P<0.01).The total score of disease cognition was negatively correlated with the total score of MUIS and CT-DAS(P<0.05),while the total score of MUIS was positively correlated with the total score of CT-DAS(P<0.05).Irregular outpatient follow-up,poor medication compliance,low MUIS score,high MUIS total score,and high CT-DAS total score were significant influencing factors for rehospitalization in patients with PHD during follow-up(P<0.05 to P<0.01).Conclusions:The low cognitive level of PHD disease,the high level of disease uncertainty and death anxiety are related to the rehospitalization of patients within 6 months after discharge.Clinical attention should be paid to health education,improve the cognition level of patients with PHD,and reduce the disease uncertainty and death anxiety.