Research Advances on COVID-19 Self-Assembled Nanoparticle Vaccine
Self-assembled nanoparticles as an antigen display platform can effectively enhance the immune effect and stability of antigens,which is a promising vaccine technology.Covid-19 epidemic has accelerated the development of particulate COVID-19 vaccines,and there are already some COVID-19 vaccines using nanoparticles in various stages of clinical trials.In this paper,the application of several self-assembled particulate antigen display platforms in the COVID-19 vaccine development is introduced,and the immune mechanisms and research progresses are reviewed.
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