杭州市流感样病例中流感病毒和肠道病毒流行特征分析
Epidemiological Characteristics of Influenza Virus and Enteroviruses Among Influenza-like Cases in Hangzhou City,China,in 2021
邱晓枫 1曹飞飞 1程实 1潘劲草 1李钧1
作者信息
- 1. 杭州市疾病预防控制中心,杭州 310021
- 折叠
摘要
本研究关注浙江省杭州市流感样病例中流感病毒(Influenza virus,IV)和肠道病毒(Enterovirus,EV)的病原谱及流行特征,为IV和EV感染防治提供了科学依据.纳入2021年杭州市流感监测哨点医院2762份流感样病例咽拭子样本,检出IV 188例(6.81％)、EV 286例(10.35％)、IV和EV共感染9例(0.33％).结果显示:IV流行季节主要是秋冬季、8～17岁年龄组可能是重点人群;EV流行季节主要是夏季、8岁以下儿童是重点人群.IV阳性率无性别差异(x2=0.122,P=0.762),EV阳性率男性高于女性(x2=18.913,P＜0.001).IV阳性样本均为乙型流感Victoria亚型.EV阳性标本中128例(44.76％)测序成功,156例(54.55％)分型成功,包括5种HEV-A、6种HEV-B、6种RV-A.IV优势基因型为BV,EV优势基因型为CVA4.2021年浙江省杭州市流感样病例中IV、EV感染具有明确的季节性和年龄特征.
Abstract
This study focuses on the pathogenic spectrum and epidemic characteristics of Influenza virus(IV)and Enterovirus(EV)in influenza-like cases in Hangzhou city,Zhejiang Province,China,providing a scientific basis for prevention and treatment of IV and EV infections.A total of 2,762 influenza-like case throat swab samples were collected from Hangzhou sentinel hospitals in 2021,of which 188 cases(6.81％)were positive for IV,286 cases(10.35％)were positive for EV,and 9 cases(0.33％)were co-infected with IV and EV.The results showed that the main season for IV circulation was autumn and winter,and the 8-17 year-old age group was the key population.The main season for EV circulation was summer,and children under 8 years old were the key population.There was no gender difference in the positivity rate of IV(x2=0.122,P=0.762).The positivity rate of EV was higher in males than females(x2=18.913,P＜0.001).All IV-positive samples belonged to the influenza B Victoria subtype.Among the EV-positive specimens,128 cases(44.76％)were successfully sequenced,and 156 cases(54.55％)were successfully typed,including 5 types of HEV-A,6 types of HEV-B,and 6 types of RV-A.The dominant genotypes of IV and EV were BV and CVA4 respectively.Influenza virus and Enterovirus infections in influenza-like cases in Hangzhou,Zhejiang Province in 2021 showed clear seasonal and age characteristics.
关键词
流感病毒/肠道病毒/流感样病例/基因型/流行特征Key words
Influenza virus/Enterovirus/Influenza-like illness/genotype/Epidemic Characteristics引用本文复制引用
基金项目
杭州市农业与社会发展科研计划(20170533B76)
杭州市"卫生微生物"医学重点学科项目()
出版年
2024
NETL
NSTL
万方数据