Epidemiological Characteristics of Influenza Virus and Enteroviruses Among Influenza-like Cases in Hangzhou City,China,in 2021
This study focuses on the pathogenic spectrum and epidemic characteristics of Influenza virus(IV)and Enterovirus(EV)in influenza-like cases in Hangzhou city,Zhejiang Province,China,providing a scientific basis for prevention and treatment of IV and EV infections.A total of 2,762 influenza-like case throat swab samples were collected from Hangzhou sentinel hospitals in 2021,of which 188 cases(6.81％)were positive for IV,286 cases(10.35％)were positive for EV,and 9 cases(0.33％)were co-infected with IV and EV.The results showed that the main season for IV circulation was autumn and winter,and the 8-17 year-old age group was the key population.The main season for EV circulation was summer,and children under 8 years old were the key population.There was no gender difference in the positivity rate of IV(x2=0.122,P=0.762).The positivity rate of EV was higher in males than females(x2=18.913,P＜0.001).All IV-positive samples belonged to the influenza B Victoria subtype.Among the EV-positive specimens,128 cases(44.76％)were successfully sequenced,and 156 cases(54.55％)were successfully typed,including 5 types of HEV-A,6 types of HEV-B,and 6 types of RV-A.The dominant genotypes of IV and EV were BV and CVA4 respectively.Influenza virus and Enterovirus infections in influenza-like cases in Hangzhou,Zhejiang Province in 2021 showed clear seasonal and age characteristics.
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