Application of Single-Cell Sequencing in the Innate Immune Response Induced by Influenza Viruses
Acute respiratory infectious diseases caused by influenza viruses can cause serious harm to public-health security and global epidemics.As the first line of defense against influenza viruses,innate immunity plays an important part in identifying and eliminating influenza viruses.Herein,we introduce the mechanism of recognition by innate immune cells of influenza viruses.We focus on the immune response of innate lymphoid cells,mononuclear macrophages,neutrophils,and dendritic cells to influenza viruses.We discuss application of single-cell sequencing in the innate immune response to provide ideas for the research and treatment of influenza viruses.