Globally,soil priming effect (PE) is regarded as a widespread process,but with equivocal directions and intensity. Multiple hypotheses of PE mechanisms were summarized,including preferential substrate utilization,co-metabolism,nutrient mining,and stoichiometric decomposition. This review also discussed abiotic and biotic factors that may regulate PE direction and intensity,which could be divided into properties of exogenous substrates,soil physicochemical characteristics,decomposers,and environmental conditions. Future researches should improve the experimental methods of simulating priming effect in natural conditions,and pay more attention to the alteration of PE direction and intensity along soil profile or time period to improve soil carbon models.