Finite element analysis of homogeneity of mixed gas in nitric oxide therapeutic apparatus
Objective To study the effects of internal pressure of gas mixing device,preset NO output concentration and input gas flow rate on gas mixture uniformity in nitric oxide therapeutic apparatus by computational fluid dynamics(CFD),and to provide reference for the safety evaluation of nitric oxide therapeutic apparatus.Methods Firstly,seven examples were set up by analyzing the working principle,working parameters and gas mixing device structure of the nitric oxide therapeutic apparatus.Then,the gas mixing device model was meshed,numerical method was chosen and the control equations were introduced.Finally,the gas mixture uniformity quantification was designed and the finite element simulation of every examples was carried out by FLUENT software.Results According to the cloud diagrams which were exported in FLUENT software and the gas mixing uniformity of every examples which were calculated by uniformity quantification formula,examples 1 to 7 were respectively 91.62%,92.75%,93.09%,92.53%,94.21%,93.98%and 97.75%.Conclusions Through comparation of each results,we found out that the influence of the internal pressure of the gas mixing device and the preset NO output concentration on the mixed gas uniformity was relatively weak,while the input gas flow rate had a large influence on the mixed gas uniformity in the nitric oxide therapeutic apparatus.This study can provide a technical reference for the safety of nitric oxide therapeutic apparatus.
computational fluid dynamicsnitric oxide therapeutic apparatusmixing uniformityfinite element simulationFLUENT