Objective The reservoir-pressure wave model ingeniously divides the arterial system's function into conduit function and storage function,introducing more variables to explain hemodynamic changes. This study aims to compare the reservoir-pressure wave model with the "gold standard" wave separation model in reflecting hemodynamic changes in patients and investigate whether the reservoir-pressure wave model is more valuable than other similar waveform analysis techniques. Methods Thirty patients undergoing general anesthesia for knee joint replacement surgery were selected. Arterial pressure waveforms were collected around the time points when hemodynamic changes occurred due to intraoperative interventions. The signals were preprocessed and analyzed using the two waveform analysis models mentioned above, incorporating waveform parameters such as reservoir-wave rising slope (Pr/tr),reservoir-wave amplitude to pulse pressure ratio (Pr/PP),position of the reservoir-wave peak in the cardiac cycle (tr/T),reverse wave rising slope (Pb/tb),etc. Pairwise sample t-tests were used to compare life sign parameters and waveform parameters before and after induction and drug administration. Spearman correlation analysis was performed between the changes in waveform parameters at five intraoperative time points and life sign parameter changes. Results Changes in life sign parameters and waveform feature parameters before and after induction and drug administration showed statistically significant differences. In the wave separation model, only the negative correlation between the upslope of the backward wave (Pb/tb) and cardiac output (CO) was significant (r=-0. 312,P<0. 05),while other parameters showed low correlations with intraoperative life sign parameters. In the reservoir-pressure wave model,the correlation coefficients of Pr/tr with CO and Pcv-aCO2 were -0. 766 and 0. 616 ( P<0. 01) ,and tr/T had a correlation coefficient of 0. 483 ( P<0. 01 ) with CO. The reservoir-pressure wave model ' s feature parameters exhibited a stronger correlation with life sign parameters. Conclusions The reservoir-pressure wave model is more valuable than similar waveform analysis techniques in reflecting hemodynamic changes in patients with hypertension.
关键词
动脉压力波形/血流动力学/生命体征参数/波分离模型/储存压力波模型
Key words
arterial pressure waveform/hemodynamics/physiological indicators/wave separation model/reservoir-pressure wave model
维普
万方数据