Mechanical properties of chitosan hydrogel based on silver ion crosslinking
Objective Chitosan (CTS) molecules in alkaline atmosphere (NH3) through molecular chain entanglement,non-covalent bond interaction and intermolecular low energy bond ( such as hydrogen bond, coordination bond,etc.) interaction,can gradually form a network structure of chitosan hydrogel (CTS/NH3). But in practice,due to the poor mechanical properties of pure chitosan hydrogel,it can be used in the field of biomaterials only after it is combined with a rigid protective gel to form a bilayer physical cross-linking. This article aims to improve its related properties by adding metal silver ions. Methods First,2. 5 g chitosan was added to 100 mL 2％ acetic acid solution to prepare 2. 5％ chitosan solution. A certain amount of silver nitrate was added to the chitosan solution to form chitosan-AgNO3 solution, and 30 mL of chitosan-AgNO3 solution was poured into the Petri dish. The Petri dish was placed in a closed environment of 0. 2 m3 containing 100 mL of ammonia water for 12 hours until the hydrogel was formed. The hydrogel was removed from the Petri dish and washed with distilled water until the washing solution was neutral to prepare chitosan-silver ion hydrogels with different silver ion concentrations. The mechanical properties were then examined by swelling properties, surface morphology, rheology and tensile properties. Results Silver ion enhanced the swelling and rheological properties of chitosan hydrogel, which significantly improved its mechanical properties. With the increase of silver ion concentration, the mechanical properties became better. Compared with pure chitosan hydrogel, the mechanical strength of chitosan hydrogel can be increased by at least 10 times with the proper addition of silver ions. Conclusions Metal silver ions can effectively improve the mechanical properties of chitosan hydrogel.
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