Current status of in vitro test methods for vascular stents fatigue performance
Stent implantation is an effective treatment of vascular surgery.In clinical,vascular stents are exposed to over 100 million cycles of pulsatile loading.Thus,during the development and registry of vascular stents,fatigue performance is one of the key factors of the safety evaluation.The establishment of an in vitro test by simulating the vascular environment in vivo has become the main means for assessing the fatigue durability performance of stents.In vitro fatigue test methods in a scientific and reasonable way are of great significance for assessing the clinical service life of stents.At present,domestic and foreign standards mainly propose requirements for the radial pulsation durability and the durability testing methods of axial,bending,and torsion non radial cyclic deformation faced by brackets in vitro fatigue testing.Some literature reports on an in vitro fatigue testing platform developed based on standard testing methods,which can help evaluate the clinical expected durability performance of stent products and determine potential failure modes.However,the current testing platform still has many limitations and there is still a certain gap compared to the real in vivo environment.In this review,the research status of fatigue tests on vascular stents at home and abroad is summarized from the perspective of fatigue test methods and fatigue test devices.
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