The influence of directionality of biological patch tissue on its mechanical properties
Objective Mechanical properties are important characteristics to ensure the clinical effectiveness of patches.Biological patches have directionality in tissue arrangement(hereinafter referred to as tissue directionality),yet the impact of this characteristic on their mechanical properties has not been studied in detail.This study intends to use allogeneic dermal matrix patches and bovine pericardium patches to test their mechanical properties in different tissue directions,providing reference for the research and development,inspection,supervision,and application of related industry products.Methods We took 6 pieces of allogeneic dermal matrix patches and 6 pieces of bovine pericardium patches,with 2 patches of the same material in each group.We cut 3 samples from each patch along the parallel and perpendicular directions to the tissue for testing the same item.By using a single column electronic tensile testing machine,we measured the tensile strength,elongation at break,suture strength,and tear strength of the two types of patches in parallel and perpendicular directions to the tissue.We used single tailed t-test to analyze whether there were differences in the test results of different organizational directions,and compared the testing phenomena of different organizational directions.Results The mechanical property tests of the two types of patches showed significant differences in tissue orientation.The tensile strength and elongation at break parallel to the tissue direction were significantly higher than those perpendicular to the tissue direction(P＜0.05),while the suture strength and tear strength were significantly lower than those perpendicular to the tissue direction(P＜0.05).And in the testing of suture strength and tear strength,the damage of the samples also showed significant differences in tissue direction.Conclusions The tissue orientation of biological patches can have an impact on their mechanical properties.Therefore,it is recommended to distinguish between them in product performance testing and evaluation in order to reflect product performance more comprehensively and promote high-quality development of the industry.
国家科技期刊平台
NSTL
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