Preparation methods and composition study of decoction of Radix Salviae Miltiorrhizae based on fingerprint chromatogram representation
Objective To investigate the influence of common preparation methods of Radix Salviae Miltiorrhizae on the changes of its chemical compositions by applying the fingerprint chromatogram, and its dissolution characteristics for different times of extraction in the decoction of Radix Salviae Miltiorrhizae. Method The changes of chemical compositions and difference between extractable compositions and original compositions of CHR were compared before and after the preparation by applying HPLC fingerprint chromatogram and the control and analytic method of chemical standard samples. Result There were only protocatechualdehyde in the material and the slices of Radix Salviae Miltiorrhizae. There was no protocatechuic acid observed, but which was found out in the stirfrying slices with wine and then the relative content of protocatechualdehyde decreased at the same time. The liposoluble compositions of the slices was dissolved out uneasily in the decoction, while the most of water-soluble compositions were extracted out after extracting for two times. Conclusion It is difficult for the liposoluble compositions of slices of Radix Salviae Miltiorrhizae to dissolve into the decoction, which indicates that the effective material base ( chemical compositions) of Radix Salviae Miltiorrhizae in the decoction should be its water-soluble compositions.
国家科技期刊平台
NSTL
万方数据
维普
