Influences of seasonal variations on T3 and T4 content and mechanism study
Objective To investigate the internal mechanism of fluctuation of T3 and T4 under the influences of seasonal variations. Methods Ten healthy volunteers were selected and the content of T3 and T4 in the blood samples collected from them were detected at 8 assigned solar terms. Meanwhile, rats were bought 40 days before the Summer Solstice and Winter Solstice, and then they were divided into the physiology group, sham-operation group and operation group according to their operation status. The rats were feed until to the day of the Summer Solstice and Winter Solstice and killed for detecting the content of T3 and T4. Results The content of T3 and T4 had significant variations in the healthy volunteers at the 8 solar terms showing higher in winter and spring, and lower in summer and autumn. The content of T3 and T4 was significantly different between two solar terms of winter and summer in rats. There was the interactions between operations and solar terms. Conclusion The thyroid hormones have changes in winter and summer in healthy people. The animal experiment has proved that the change laws of thyroid hormones, showing higher in winter and lower in summer, are correlated closely to the up-regulation mechanism of pineal gland.
国家科技期刊平台
NSTL
万方数据
